Do high-voltage pulses cause changes in skin structure?
Do high-voltage pulses cause changes in skin structure?
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DOI：
10.1016/0168-3659(95)00199-9
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发表时间：
1996-07-01
影响因子：
10.8
通讯作者：
Prausnitz, MR
中科院分区：
文献类型：
--
作者：
Prausnitz, MR
皮肤特性的剧烈变化是由高压脉冲（例如，100 V）毫秒持续时间。这些变化发生的确切机制尚未解决，但可能是由于皮肤结构的改变，可能涉及角质层细胞内脂质双层的电穿孔。支持这一假设的证据是从一系列的研究，解决分子传输，电阻抗，显微成像和理论分析。
Dramatic changes in skin properties are caused by high-voltage pulses (e.g., 100 V) of millisecond duration. The exact mechanism by which these changes occur remains unresolved, but may result from alterations of skin structure, possibly involving electroporation of the stratum corneum's intracellular lipid bilayers. The evidence supporting this hypothesis is presented from a range of studies which address molecular transport, electrical impedance, microscopic imaging and theoretical analysis.