A prospective controlled study: minimally invasive stereotactic puncture therapy versus conventional craniotomy in the treatment of acute intracerebral hemorrhage.
A prospective controlled study: minimally invasive stereotactic puncture therapy versus conventional craniotomy in the treatment of acute intracerebral hemorrhage.
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一项前瞻性对照研究：微创立体定向穿刺疗法与传统开颅手术治疗急性脑出血的比较。
DOI：
10.1186/1471-2377-11-76
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发表时间：
2011-06-23
期刊：
影响因子：
2.6
通讯作者：
Dong Q
中科院分区：
文献类型：
--
作者：
Zhou H;Zhang Y;Liu L;Han X;Tao Y;Tang Y;Hua W;Xue J;Dong Q
自发性脑出血(ICH)是一种破坏性的卒中类型，其病死率是缺血性卒中的2~6倍。但基底节内血肿的治疗在神经学家和神经外科医生之间仍然是一个有争议的问题。本研究旨在评价微创立体定向穿刺术(MISPT)治疗急性脑出血的临床价值。进行了一项前瞻性对照研究。该临床试验符合WMA赫尔辛基宣言--涉及人类受试者的医学研究伦理原则。按入选标准分析急性脑出血168例，其中MISPT组90例(MISPT组)，常规开颅手术78例(CC组)，比较格拉斯哥昏迷评分(GCS)、术后并发症(PC)和再出血率(RI)，并以格拉斯哥预后评分(GOS)、Barthel指数(BI)、改良Rankin评分(MRS)和病死率(CF)判断术后1年的远期预后。MG患者的GCS评分较对照组有明显改善。MG组PC的总发生率明显低于CG组。再出血率分别为10.0%和15.4%。MG组和CG组的CFs无明显差异。在反映远期预后的3项指标中，MG组的GOS、BI和MRS均较对照组有显著改善。这些数据表明，MISPT的优势表现在微创和安全方面，似乎是可行的，并有改善长期疗效的趋势。澳大利亚新西兰临床试验注册中心(ANZCTR)，注册号：ACTRN12610000945022。
Spontaneous intracerebral hemorrhage (ICH) is a devastating form of stroke with the high mortality twofold to sixfold higher than that for ischemic stroke. But the treatment of haematomas within the basal ganglia continues to be a matter of debate among neurologists and neurosurgeons. The purpose of this study is to judge the clinical value of minimally invasive stereotactic puncture therapy (MISPT) on acute ICH. A prospective controlled study was undertaken. The clinical trial was in compliance with the WMA Declaration of Helsinki - Ethical Principles for Medical Research Involving Human Subjects. According to the enrollment criterion, there were 168 acute ICH cases analyzed, of which 90 cases were performed by MISPT ( MISPT group, MG) and 78 cases by Conventional craniotomy (CC group, CG), by means of compare of Glasgow Coma Scale(GCS) score, postoperative complications(PC) and rebleeding incidence(RI), moreover, long-term outcome of 1 year postoperation judged by Glasgow Outcome Scale (GOS), Barthel Index (BI), modified Rankin Scale (mRS) and case fatality(CF). MG patients showed obvious amelioration in GCS score compared with that of CG. The total incidence of PC in MG decreased obviously compared with that of CG. The incidences of rebleeding in MG and CG were 10.0% and 15.4% respectively. There was no obvious difference between CFs of MG and CG. For three parameters representing long-term outcome, the GOS, BI and mRS in MG were ameliorated significantly than that of CG. These data suggested that the advantage of MISPT was displayed in minute trauma and safety, and seemed to be feasible and to had a trend towards improved long-term outcome. The Australian New Zealand Clinical Trials Registry (ANZCTR), the registration number:ACTRN12610000945022.
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影响因子：
8.3
作者：
Montes, JM;Wong, JH;Awad, IA
通讯作者：
Awad, IA
影响因子：
--
作者：
Marquardt, G;Wolff, R;Seifert, V
通讯作者：
Seifert, V
影响因子：
5.1
作者：
Peng, S. -Y.;Chuang, Y. -C.;Tseng, K. -H.
通讯作者：
Tseng, K. -H.
影响因子：
11
作者：
ANDERSON, CS;CHAKERA, TMH;JAMROZIK, KD
通讯作者：
JAMROZIK, KD
影响因子：
3.5
作者：
Barrett, RJ;Hussain, R;Carhuapoma, JR
通讯作者：
Carhuapoma, JR