Characterization of Coronary Flow Reserve and Left Ventricular Remodeling in a Mouse Model of Chronic Aortic Regurgitation With Carvedilol Intervention

Characterization of Coronary Flow Reserve and Left Ventricular Remodeling in a Mouse Model of Chronic Aortic Regurgitation With Carvedilol Intervention
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DOI:
10.7863/ultra.34.3.483
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发表时间:
2015-03
影响因子:
2.3
通讯作者:
Xiang-fei Wang;Jian Wu;D. Zhu;J. You;Y. Zou;J. Qian;J. Ge
Xiang-fei Wang;Jian Wu;D. Zhu;J. You;Y. Zou;J. Qian;J. Ge
中科院分区:
医学4区
文献类型:
--
作者:
Xiang-fei Wang;Jian Wu;D. Zhu;J. You;Y. Zou;J. Qian;J. Ge

文献摘要

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我们假设慢性重度主动脉瓣反流小鼠的冠状动脉血流储备受损可能会加剧左心室(LV)重塑,卡维地洛(一种β肾上腺素受体阻滞剂)可能会逆转该过程。
We hypothesized that left ventricular (LV) remodeling might be exaggerated by an impaired coronary flow reserve in mice with chronic severe aortic regurgitation, and carvedilol, a β‐adrenoceptor blocker, could regress the course.