Surface enhanced Raman scattering of biospecies on anodized aluminum oxide films

Surface enhanced Raman scattering of biospecies on anodized aluminum oxide films
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DOI:
10.1016/j.cplett.2007.04.041
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发表时间:
2007-06-08
影响因子:
2.8
通讯作者:
Grebel, H.
Grebel, H.
中科院分区:
化学4区
文献类型:
--
作者:
Zhang, C.;Smirnov, A. I.;Grebel, H.

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传统上,铝和阳极氧化铝膜(AAO)不是表面增强拉曼散射(Sers)实验的选择平台,尽管铝的大的负介电常数值。在这里,我们研究了铝和纳米多孔氧化铝平台的有用性,用于检测从细菌孢子到蛋白质标记物的软生物物种。我们使用这些平坦的平台来检查模型蛋白(来自牛心脏组织的细胞色素c)和细菌细胞(用作炭疽模拟物的枯草芽孢杆菌ATCC 13933的孢子)的Sers,并证明了清晰的拉曼扩增。(C)2007 Elsevier B.V.保留所有权利。
Traditionally, aluminum and anodized aluminum oxide films (AAO) are not the platforms of choice for surface-enhanced raman scattering (SERS) experiments despite of the aluminum's large negative permittivity value. Here we examine the usefulness of aluminum and nanoporous alumina platforms for detecting soft biospecies ranging from bacterial spores to protein markers. We used these flat platforms to examine SERS of a model protein (cytochrome c from bovine heart tissue) and bacterial cells (spores of Bacillus subtilis ATCC13933 used as Anthrax simulant) and demonstrated clear Raman amplification. (C) 2007 Elsevier B.V. All rights reserved.