POLYCHLORINATED-BIPHENYLS (PCBS) AND DICHLORODIPHENYL DICHLOROETHENE (DDE) IN HUMAN-MILK - EFFECTS ON GROWTH, MORBIDITY, AND DURATION OF LACTATION
POLYCHLORINATED-BIPHENYLS (PCBS) AND DICHLORODIPHENYL DICHLOROETHENE (DDE) IN HUMAN-MILK - EFFECTS ON GROWTH, MORBIDITY, AND DURATION OF LACTATION
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DOI：
10.2105/ajph.77.10.1294
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发表时间：
1987-10-01
影响因子：
12.7
通讯作者：
TULLY, M
中科院分区：
文献类型：
--
作者：
ROGAN, WJ;GLADEN, BC;TULLY, M
我们跟踪了858名从出生到一岁的儿童，以确定母乳中多氯联苯（PCB）和二氯二苯二氯乙烯（DDE）的存在是否会影响他们的生长或健康。这两种化学物质都没有对体重或因各种疾病去看医生的频率产生不利影响，尽管母乳喂养和奶瓶喂养的儿童之间存在差异，奶瓶喂养的儿童体重更重，患胃肠炎和中耳炎的频率更高。DDE水平较高的母亲的孩子母乳喂养的时间明显较短，但调整可能的混杂因素和偏见并没有改变结果。在对儿童健康没有任何明显影响的情况下，我们推测DDE可能会干扰母亲的泌乳能力，可能是因为其雌激素特性。
We followed 858 children from birth to one year of age of determine whether the presence of polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in breast milk affected their growth or health. Neither chemical showed an adverse effect on weight or frequency of physican visits for various illnesses, although differences were seen between breast-fed and bottle-fed children, with bottle-fed children being heavier and having more frequent gastroenteritis and otitis media. Children of mothers with higher levels of DDE were breast-fed for markedly shorter times, but adjustments for possible confounders and biases did not change the findings. In absence of any apparent effect on the health of the children, we speculate that DDE may be interfering with the mother''s ability to lactate, possibly because of its estrogenic properties.