A NEW METHOD OF SCORING CORONARY ANGIOGRAMS TO REFLECT EXTENT OF CORONARY ATHEROSCLEROSIS AND IMPROVE CORRELATION WITH MAJOR RISK-FACTORS

A NEW METHOD OF SCORING CORONARY ANGIOGRAMS TO REFLECT EXTENT OF CORONARY ATHEROSCLEROSIS AND IMPROVE CORRELATION WITH MAJOR RISK-FACTORS
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DOI:
10.1016/s0002-8703(05)80173-5
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发表时间:
1990-06-01
影响因子:
4.8
通讯作者:
FREEDMAN, SB
FREEDMAN, SB
中科院分区:
医学2区
文献类型:
--
作者:
SULLIVAN, DR;MARWICK, TH;FREEDMAN, SB

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我们开发了一种新的冠状动脉病变程度的血管造影评分(程度评分),并将其与强调狭窄严重程度的传统狭窄和血管评分进行了比较。对132名患者(29名女性,103名男性,平均年龄为55 ± 10岁)进行了评分。10年),接受了择期冠状动脉造影术。危险因素与狭窄程度评分的关系比与狭窄或血管评分的关系更密切(总R2分别为0.35与0.28(p < 0.001)和0.25(p < 0.001))。与狭窄(r = 0.21 ns)或血管评分(r = 0.26,p < 0.05)相比,范围评分与年龄的关系更为密切(r = 0.30,p < 0.05)。载脂蛋白B是范围和狭窄评分的最强预测因子,但与范围评分更密切相关(r = 0.36,p < 0.05),即使校正了年龄和性别。这种评估冠状动脉疾病程度的血管造影评分操作简单,并且与年龄和脂蛋白风险因素的相关性优于传统评分。
We developed a new angiographic score of the extent of coronary disease (extent score), which we compared with conventional stenosis and vessel scores that emphasize the severity of stenosis. Scores were determined in 132 patients (29 women, 103 men with a mean age of 55 .+-. 10 years) who underwent elective coronary angiography. Risk factors were more closely related to the extent score than to either the stenosis or vessel scores (Total R2 = 0.35 versus 0.28 (p < 0.001) and 0.25 (p < 0.001), respectively). The extent score was more closely related to age (r = 0.30, p < 0.05), than was either stenosis (r = 0.21 ns) or vessel score (r = 0.26, p < 0.05). Apolipoprotein B was the strongest predictor of both extent and stenosis scores but was more closely related to the extent score (r = 0.36, p < 0.05), even after correction for age and gender. This angiographic score that assesses the extent of coronary disease is simple to perform and correlates better with age and lipoprotein risk factors than conventional scores do.