Clinicopathologic and the imaging manifestations of central neurocytoma
Clinicopathologic and the imaging manifestations of central neurocytoma
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发表时间：
2004
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通讯作者：
L. Bo
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作者：
L. Bo
目的探讨中枢神经细胞瘤的临床病理及影像学特点，以提高诊断水平。材料与方法回顾性分析6例CNC的临床资料，并结合病理特点进行分析.结果男4例，女2例，年龄30 ~ 63岁，平均45岁。肿瘤主要位于侧脑室靠近Monra孔处，基底较宽，附着于侧脑室侧壁或透明隔。CT表现为等信号或稍高信号肿块，其内可见多发小囊性影及斑片状钙化。T1 WI呈等或稍低信号，T2 WI呈不均匀高信号，增强后轻至中度强化。免疫组化结果显示突触素、突触素、胶质细胞酸性蛋白、GFAP、神经元特异性包被酶、NSE均呈阳性。结论脑室前区或靠近Monra孔的肿瘤多见，其影像学表现具有特征性。如果肿瘤发生在特定区域，应考虑CNC。
Objective To explore the clinicopathologic and the imaging features of central neurocytomaCNC in order to improve the diagnosis. Materials and Methods Six cases of CNC were analyzed retrospectively also correlate with pathological features. Results There were 4 males and 2 females and the age ranged from 30 to 63 years oldthe mean age was 45 years old. The tumors were primarily located in the lateral ventricles close to the foramina of Monra and attached to the lateral wall of the lateral ventricle or septum pellucidum with a broad base. CT scan displayed isointense or slightly hyperintense mass with multiple small cystic features and patch like calcifications. The tumors revealed isointense or slightly hypointense signal on T1WI and heterogeneous hyperintense signal on T2WI with slight to moderate enhancement. Results of immunohistochemical study were positive for synptophysinSyn glial fibrillary acid proteinGFAP and neuron specific enclaseNSE. Conclusion The tumors were mainly located in the anterior region of ventricles or close to the foramina of Monra and their imaging features were characteristic. CNC should be taken into consideration if tumor arises from the specific region.