Laser interstitial thermal therapy in gliomas
Laser interstitial thermal therapy in gliomas
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DOI：
10.1016/j.canlet.2020.01.024
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发表时间：
2020-01-01
期刊：
影响因子：
9.7
通讯作者：
Nakaji, Peter
中科院分区：
文献类型：
--
作者：
Bozinov, Oliver;Yang, Yang;Nakaji, Peter
激光间质热疗（LITT）作为一种微创治疗方法已用于脑转移瘤、癫痫和坏死以及胶质瘤多年。随着热监测和消融精度的提高，特别是磁共振（MR）热成像技术在手术中的应用以及目前已有的两种商用激光系统，LITT逐渐被更多的神经外科中心所接受。近年来，一些新的概念被提出，如LITT后的辅助化疗或放疗，LITT与免疫治疗的联合应用等。本研究的目的是总结LITT特别是脑胶质瘤的进展和未来的可能展望。
Laser interstitial thermal therapy (LITT) has been used for brain metastasis, epilepsy, and necrosis, as well as gliomas as a minimally invasive treatment for many years. With the improvement of the thermal monitoring and ablation precision, especially the application of magnetic resonance (MR) thermography in the procedure and the available two commercial laser systems nowadays, LITT is gradually accepted by more neurosurgical centers. Recently, some new concepts, for example the adjuvant chemotherapy or radiation following LITT, the combination of immunotherapy and LITT regarding the glioma treatment are proposed and currently being investigated. The aim of this study is to summarize the evolution of LITT especially for brain gliomas and a possible outlook of the future.