Aerobic selective oxidation of (hetero) aromatic primary alcohols to aldehydes or carboxylic acids over carbon supported platinum
Aerobic selective oxidation of (hetero) aromatic primary alcohols to aldehydes or carboxylic acids over carbon supported platinum
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DOI：
10.1016/j.apcatb.2006.01.029
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发表时间：
2007-01-31
影响因子：
22.1
通讯作者：
Besson, Michele
中科院分区：
文献类型：
--
作者：
Donze, Cecile;Korovchenko, Pavel;Besson, Michele
在 1.95 wt.% PUC 催化剂存在下，在温和压力（< 20 bar）和 100 摄氏度下，通过用空气氧化芳香醇，研究了取代苯甲醛、苯甲酸、杂环芳香醛和酸的合成。发现溶剂在确定氧化产物的选择性方面发挥着最重要的作用。改变溶剂可以将反应调节为醛（纯二恶烷）或羧酸（二恶烷/水溶液，不添加或添加氢氧化钠）。这种氧化方法可以有效氧化许多具有各种电子释放或吸电子基团（NO2、Me、OMe、Cl、Br、OH、苯基等）的取代苯甲醇和包含氮和硫原子的杂环醇（2-噻吩甲醇、2-和4-吡啶甲醇化合物）。 (c) 2006 Elsevier B.V. 保留所有权利。
The synthesis of substituted benzaldehydes, benzoic acids, heterocyclic aromatic aldehydes and acids has been studied via the oxidation of the aromatic alcohols with air under mild pressure (< 20 bar) at 100 degrees C, in the presence of a 1.95 wt.% PUC catalyst. The solvent was found to play the most important role in determining the selectivity of the oxidation products. Changing the solvent enabled tuning the reaction either to the aldehyde (pure dioxane), or the carboxylic acid (dioxane/aqueous solution without or with addition of sodium hydroxide). This oxidation method allowed to effectively oxidize many substituted benzylalcohols with various electron-releasing or -attracting groups (NO2, Me, OMe, Cl, Br, OH, phenyl,...) and heterocyclic alcohols including nitrogen and sulphur atoms (2-thiophenemethanol, 2- and 4-pyridine methanol compounds). (c) 2006 Elsevier B.V. All rights reserved.