Reporting animal use in scientific papers
Reporting animal use in scientific papers
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DOI：
10.1258/002367797780596176
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发表时间：
1997-10-01
影响因子：
2.4
通讯作者：
Sadler, D
中科院分区：
文献类型：
--
作者：
Smith, JA;Birke, L;Sadler, D
本文报告了一系列生物医学实验研究论文的“方法”部分的检查结果，重点是动物使用和住房的描述。方法中的详细说明应能供复制，并使读者能够判断其科学质量。相对较少的论文抽样充分描述了住房条件，许多未能提供生理相关的细节：变量，如动物的体重。30%的论文遗漏了所用动物的数量，动物的死亡（无论是作为实验方案的一部分，还是意外死亡）并不总是被记录下来，充分报告动物的饲养和使用条件是很重要的，这既关系到所产生的科学的质量，也因为公众对动物实验伦理的关注。
This paper reports the results of an examination of the 'methods' sections of a range of experimental research papers in biomedical science, focusing on the descriptions of animal use and housing. Detailed descriptions in the methods should enable replication, and also enable readers to judge scientific quality. Relatively few papers sampled gave adequate descriptions of housing conditions and many failed to give details of physiologically relevant: variables such as weight of animals. Thirty per cent of papers omitted the number of animals used, and the deaths of animals (whether as part of the protocol, or accidental death) were not always recorded.Adequate reporting of the conditions of animal maintenance and use are important, both in relation to the quality of the science produced, and also because of public concerns about the ethics of animal experiments.