Wireless capsule endoscopy of the small bowel: development, testing, and first human trials
Wireless capsule endoscopy of the small bowel: development, testing, and first human trials
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DOI：
10.1117/12.413789
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发表时间：
2001-01
期刊：
影响因子：
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通讯作者：
P. Swain;G. Iddan;G. Meron;A. Glukhovsky
中科院分区：
文献类型：
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作者：
P. Swain;G. Iddan;G. Meron;A. Glukhovsky
使用现有内窥镜进行的小肠内窥镜检查受到不适问题和深入小肠的技术难度的限制。我们的目标是开发和测试无线胶囊内窥镜检查。胶囊形式的无线内窥镜（11 x 33 毫米）由 Give Imaging 制造。它们由氧化银电池供电，每个都包含 CMOS 成像芯片和微型处理器、白光发光二极管 (LED)、短焦距镜头以及微型发射器和天线。使用射频（约 410 MHz）将每秒两个视频帧传输到附着在身体上的天线阵列。天线阵列还可用于计算胶囊在体内的位置。图像存储在腰带上的便携式记录仪上，随后下载进行分析。尽管胶囊通常在两小时内穿过整个小肠，但电池可以进行超过 5 小时的记录。记录了从幽门到盲肠的人类肠道的清晰视频图像。无线内窥镜首次实现了整个小肠的无痛光学成像。
Small bowel endoscopy with existing endoscopes is limited by problems of discomfort and the technical difficulty of advancing far into the small-bowel. Our aim has been to develop and test wireless capsule endoscopy. Wireless endoscopes, in the form of capsules (11 x 33 mm), were constructed by Given Imaging. These were powered by silver oxide batteries and each contained a CMOS imaging chip and miniature processor, white light emitting diodes (LEDs), a short focal length lens, and a miniature transmitter and antenna. Two video frames per second were transmitted, using radio-frequency (approx. 410 MHz), to an array of aerials attached to the body. The array of aerials can also be used to calculate the position of the capsule in the body. The images were stored on a portable recorder carried on a belt and subsequently downloaded for analysis. The batteries allow more than 5 hours of recording, although the capsule generally passes through the whole small bowel in under two hours. Clear video images of the human bowel were recorded from the pylorus to the caecum. Wireless endoscopy, for the first time, allows painless optical imaging of the whole of the small bowel.