An alkoxide-directed intermolecular [2+2+1] annulation:: A three-component coupling reaction for the synthesis of tetrasubstituted α,β,-unsaturated γ-lactams

An alkoxide-directed intermolecular [2+2+1] annulation:: A three-component coupling reaction for the synthesis of tetrasubstituted α,β,-unsaturated γ-lactams
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DOI:
10.1002/anie.200605060
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发表时间:
2007-01-01
影响因子:
16.6
通讯作者:
Micalizio, Glenn C.
Micalizio, Glenn C.
中科院分区:
化学1区
文献类型:
--
作者:
McLaughlin, Martin;Takahashi, Masayuki;Micalizio, Glenn C.

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A regio- and stereoselective cross-coupling reaction is described between internal alkynes and imines that provides selective access to allylic amines and γ-lactams.