3D myocardial tissue tracking with slice followed cine DENSE MRI
3D myocardial tissue tracking with slice followed cine DENSE MRI
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DOI：
10.1002/jmri.21317
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发表时间：
2008-05-01
影响因子：
4.4
通讯作者：
Epstein, Frederick H.
中科院分区：
文献类型：
--
作者：
Spottiswoode, Bruce S.;Zhong, Xiaodong;Epstein, Frederick H.
目的：为了跟踪三维（3D）心肌组织运动，使用切片跟随电影位移编码成像与刺激回波（DENSE）。材料和方法：切片跟随（SF）先前已开发用于2D心肌标记，以补偿通过平面运动对2D组织跟踪的影响。通过将SF合并到电影DENSE序列中，并在三个正交方向上应用位移编码，我们证明了随着心脏在心动周期中移动，在3D中跟踪心肌切片的离散元素的能力。SF电影密度跟踪算法进行了验证，在一个移动的幻影，并通过平面运动对2D心脏应变的影响进行了研究，在六个健康subjects.Results：通过平面跟踪精度为0.46 +/- 0.32毫米测量一个典型的范围内的心肌运动使用旋转幻影。心脏运动的体内3D测量结果与先前的心肌标记结果一致。在心室短轴切面上，平面旋转可使2D收缩末期环向应变降低3.91 ± 0.43%，径向应变增加6.01 ± 1.07%。结论：层片跟随线索的DENSE技术可用于三维组织追踪。
Purpose: To track three-dimensional (3D) myocardial tissue motion using slice followed cine displacement encoded imaging with stimulated echoes (DENSE).Materials and Methods: Slice following (SF) has previously been developed for 2D myocardial tagging to compensate for the effect of through-plane motion on 2D tissue tracking. By incorporating SF into a cine DENSE sequence, and applying displacement encoding in three orthogonal directions, we demonstrate the ability to track discrete elements of a slice of myocardium in 3D as the heart moves through the cardiac cycle. The SF cine DENSE tracking algorithm was validated on a moving phantom, and the effects of through-plane motion on 2D cardiac strain were investigated in six healthy subjects.Results: A through-plane tracking accuracy of 0.46 +/- 0.32 mm was measured for a typical range of myocardial motion using a rotating phantom. In vivo 3D measurements of cardiac motion were consistent with prior myocardial tagging results. Through-plane rotation in a mid-ventricular-short-axis view was shown to decrease the magnitude of the 2D end-systolic circumferential strain by 3.91 +/- 0.43% and increase the corresponding radial strain by 6.01 +/- 1.07%.Conclusion: Slice followed clue DENSE provides an accurate method for 3D tissue tracking.