Prospective Motion Correction for Magnetic Resonance Spectroscopy Using Single Camera Retro-Grate Reflector Optical Tracking
Prospective Motion Correction for Magnetic Resonance Spectroscopy Using Single Camera Retro-Grate Reflector Optical Tracking
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DOI：
10.1002/jmri.22467
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发表时间：
2011-02-01
影响因子：
4.4
通讯作者：
Ernst, Thomas
中科院分区：
文献类型：
--
作者：
Andrews-Shigaki, Brian C.;Armstrong, Brian S. R.;Ernst, Thomas
目的：介绍并评价一种利用单相机光学跟踪系统对质子磁共振波谱（1H-MRS）进行前瞻性运动校正的方法。材料和方法：使用带有运动跟踪模块和相位导航器的点分辨光谱序列（PRESS）对5名健康参与者进行3T扫描。头部运动在6度被跟踪与一个Retro-Grate Reflector （RGR）跟踪系统和目标通过一个镜子安装在膛内。在扫描过程中，参与者执行一系列预定的三种运动模式。结果：左右旋转（Rz）（平均12度）导致未校正扫描总胆碱与总肌酸比值（Cho/Cr）增加+14.6 +/- 1.5% (P = 0.0009)，校正扫描无变化（+1.1 +/- 1.5%,P = 0.76）。未校正的z平移光谱显示大的脂质峰（颅骨），Cho/Cr变化为-13.2 +/- 1.6% （P = 0.02，无运动校正），校正后为-2.2 +/- 2.4% （P = 0.51）。与所有实验的基线扫描相比，n -乙酰天冬氨酸、谷氨酸+谷氨酰胺或肌醇与肌酸的比值没有显著变化。结论：采用单相机RGR跟踪的1H-MRS前瞻性运动校正可以减少头部运动引起的光谱伪影和Cho/Cr比的定量误差，并有望提高光谱质量和再现性。
Purpose: To introduce and evaluate a method of prospective motion correction for localized proton magnetic resonance spectroscopy (1H-MRS) using a single-camera optical tracking system.Materials and Methods: Five healthy participants were scanned at 3T using a point-resolved spectroscopic sequence (PRESS) with a motion-tracking module and phase navigator. Head motion in six degrees was tracked with a Retro-Grate Reflector (RGR) tracking system and target via a mirror mounted inside the bore. Participants performed a series of three predetermined motion patterns during scanning.Results: Left-right rotation (Rz) (average 12 degrees) resulted in an increase in the total choline to total creatine ratio (Cho/Cr) of +14.6 +/- 1.5% (P = 0.0009) for scans without correction, but no change for scans with correction (+1.1 +/- 1.5%; P = 0.76). Spectra with uncorrected Z-translations showed large lipid peaks (skull) with changes in Cho/Cr of -13.2 +/- 1.6% (P = 0.02, no motion correction) and -2.2 +/- 2.4% (P = 0.51) with correction enabled. There were no significant changes in the ratios of N-acetylaspartate, glutamate+glutamine, or myo-inositol to creatine compared to baseline scans for all experiments.Conclusion: Prospective motion correction for 1H-MRS, using single-camera RGR tracking, can reduce spectral artifacts and quantitation errors in Cho/Cr ratios due to head motion and promises improved spectral quality and reproducibility.