Securinega alkaloids from the wood of Securinega suffruticosa var. amamiensis.
Securinega alkaloids from the wood of Securinega suffruticosa var. amamiensis.
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DOI：
10.1021/np0780102
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发表时间：
2007-12
影响因子：
5.1
通讯作者：
A. Ohsaki;Yukino Kobayashi;K. Yoneda;Akio Kishida;Haruaki Ishiyama
中科院分区：
文献类型：
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作者：
A. Ohsaki;Yukino Kobayashi;K. Yoneda;Akio Kishida;Haruaki Ishiyama
从日本药用植物叶下珠Securinega suffruticosa var.的木材中分离得到三个新的叶下珠生物碱，命名为secu'amamines B-D（1- 3）。amamiensis，连同五个已知的类似物（4，6- 9）。通过包括2D NMR的光谱方法对结构1- 3进行了鉴定，并评价了所有八个化合物对两种癌细胞系的细胞毒性。
Three new Securinega alkaloids, secu'amamines B-D ( 1- 3), were isolated from the wood of the Japanese medicinal plant Securinega suffruticosa var. amamiensis, together with five known analogues ( 4, 6- 9). The structures 1- 3 were elucidated by spectroscopic methods including 2D NMR, and all eight compounds were evaluated for cytotoxicity against two cancer cell lines.