Body Mass Index and Pediatric Asthma Outcomes

Body Mass Index and Pediatric Asthma Outcomes
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体重指数和小儿哮喘结果

DOI:
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发表时间:
2009
影响因子:
1.4
通讯作者:
R. Sinert
R. Sinert
中科院分区:
医学4区
文献类型:
--
作者:
J. Hom;E. Morley;P. Sasso;R. Sinert

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目的:本研究的目的是确定哮喘儿童的体重指数(BMI)(肥胖的一种衡量指标)与急诊入院率之间的关系。方法:这是一项前瞻性研究,在三级保健,城市儿科急诊科。治疗医生和学术助理在2005年6月至2008年4月期间招募受试者。有记录的体重和身高的合格受试者年龄在6至18岁之间,主诉为喘息。我们比较了超重儿童(BMI,≥ 85%百分位数)和非超重儿童(BMI,<85%百分位数)的入院率。数据表示为平均值(SD)。适当时,通过Student t检验或Fisher精确检验进行组间比较。所有检验均为双尾检验,设定值为0.05。&agr;结果:我们研究了183名儿童,其中108名儿童被归类为超重。超重和非超重儿童之间的人口统计学差异(平均年龄,男性性别和非洲裔美国人种族)没有统计学意义。此外,哮喘结局指标的变化(前一年的住院率、过去30天的哮喘就诊率和过去30天的缺课率)无统计学显著性。只有家庭烟草使用接近统计学意义(P = 0.07)。非超重儿童的入院率为9.3%(95%置信区间[CI],4.3 - 18.3),超重儿童的入院率为10.2%(95% CI,5.6 - 17.5); P = 1.0。结论:体重指数是一种量化超重儿童的方法,但它未能预测到儿科急诊室就诊的非卧床哮喘儿童的入院情况。
Objective: The purpose of this study was to determine the association between body mass index (BMI), a measure of obesity, with emergency department admission rate in children with asthma. Methods: This was a prospective study in a tertiary care, urban pediatric emergency department. Treating physicians and academic associates enrolled subjects during June 2005 to April 2008. Eligible subjects with documented weight and height were between ages 6 and 18 years with chief complaint of wheezing. We compared admission rates between overweight children (BMI, ≥85% percentile) and nonoverweight children (BMI, <85% percentile). Data were expressed as mean (SD). Group comparisons were made by Student t test or Fisher exact test, as appropriate. All tests were 2-tailed with an &agr; set at 0.05. Result: We studied 183 children, where 108 children were classified overweight. Demographic differences (mean age, male sex, and African-American race) between overweight and nonoverweight children were not statistically significant. In addition, changes in asthma outcome measures (inpatient admissions during the previous year, asthma visits in the last 30 days, and missed school days in the last 30 days) were not statistically significant. Only household tobacco use approached statistical significance (P = 0.07). The admission rate for nonoverweight children was 9.3% (95% confidence interval [CI], 4.3-18.3) compared with the 10.2% (95% CI, 5.6-17.5) for overweight children; a P = 1.0 was equivalent. Conclusions: Body mass index, a method to quantify overweight children, failed to predict admission of children with ambulatory asthma who presented to the pediatric emergency department.