3D Quantitative Synthetic MRI in the Evaluation of Multiple Sclerosis Lesions
3D Quantitative Synthetic MRI in the Evaluation of Multiple Sclerosis Lesions
复制标题
DOI：
10.3174/ajnr.a6930
复制
发表时间：
2021-03-01
影响因子：
3.5
通讯作者：
Aoki, S.
中科院分区：
文献类型：
--
作者：
Fujita, S.;Yokoyama, K.;Aoki, S.
三维合成MR成像可以作为一种替代传统的MR成像在评估MS与减少scan time.Background和Purpose：合成MR成像创建多个对比加权图像的基础上，一个单一的时间效率的定量扫描，这主要是执行2D采集。我们评估了3D合成MR成像在MS患者中的实用性，通过比较其诊断图像质量和病变体积与常规MR imaging.MATERIALS和METHODS：24例MS患者前瞻性地进行了3D定量合成MR成像和常规T1加权，T2加权，FLAIR，和双反转恢复成像，与采集时间为9？三分钟？18秒？27分钟？对于合成MR成像和常规MR成像序列，分别为2.5秒。为合成MR成像创建合成相敏反转恢复图像和对应于常规MR成像对比度的图像。两名神经放射科医生独立评估图像质量的5点李克特量表。结果：合成T1 WI和双反转恢复图像的总体诊断图像质量不劣于常规图像（P =.. 23和.20），而合成T2 WI和FLAIR序列的显示效果均低于常规序列（P均< 0.05）。
Three-dimensional synthetic MR imaging could serve as an alternative to conventional MR imaging in evaluating MS with a reduced scan time.BACKGROUND AND PURPOSE:Synthetic MR imaging creates multiple contrast-weighted images based on a single time-efficient quantitative scan, which has been mostly performed for 2D acquisition. We assessed the utility of 3D synthetic MR imaging in patients with MS by comparing its diagnostic image quality and lesion volumetry with conventional MR imaging.MATERIALS AND METHODS:Twenty-four patients with MS prospectively underwent 3D quantitative synthetic MR imaging and conventional T1-weighted, T2-weighted, FLAIR, and double inversion recovery imaging, with acquisition times of 9?minutes 3?seconds and 18?minutes 27?seconds for the synthetic MR imaging and conventional MR imaging sequences, respectively. Synthetic phase-sensitive inversion recovery images and those corresponding to conventional MR imaging contrasts were created for synthetic MR imaging. Two neuroradiologists independently assessed the image quality on a 5-point Likert scale. The numbers of cortical lesions and lesion volumes were quantified using both synthetic and conventional image sets.RESULTS:The overall diagnostic image quality of synthetic T1WI and double inversion recovery images was noninferior to that of conventional images (P?=?.23 and .20, respectively), whereas that of synthetic T2WI and FLAIR was inferior to that of conventional images (both Ps?