Cells in the rat auditory system have sensory-delay correlates during the performance of an auditory working memory task.
Cells in the rat auditory system have sensory-delay correlates during the performance of an auditory working memory task.
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大鼠听觉系统中的细胞在执行听觉工作记忆任务期间具有感觉延迟相关性。
作者：
Y. Sakurai
记录大鼠听觉皮层（AC）、内侧膝状体（MGB）和下丘（IC）在连续非匹配样本任务中的单单位活动。老鼠做出go和no-go反应，以表明当前的音调与前一个音调相同（匹配）还是不同（不匹配）。AC，MGB和IC的31%和55%之间的单位表现出感觉相关性（两种类型的音调活动的差异），表明参与感觉辨别。AC和MGB中有20%的单位具有延迟相关性（在音调后立即延迟期间持续的差异活动），表明参与保留。大多数与延迟相关的单位也有感觉相关。这些结果表明，听觉系统，特别是AC和MGB，在听觉工作记忆中辨别和保留听觉刺激。
Single unit activity was recorded from rat auditory cortex (AC), medial geniculate body (MGB), and inferior colliculus (IC) during performance of a continuous nonmatching-to-sample task. The rats made go and no-go responses to indicate whether the current tone was the same as (match) or different from (nonmatch) the preceding tone. Between 31% and 55% of the units from AC, MGB, and IC showed sensory correlates (differences in activity to the two types of tones), indicating an involvement in sensory discrimination. Twenty percent of the units from AC and MGB had delay correlates (sustained differential activity during the delay immediately after the tones), indicating an involvement in retention. Most of the units with delay correlates also had sensory correlates. These results suggest that the auditory system, especially AC and MGB, discriminates and retains auditory stimuli in an auditory working memory.