Emerging Environmental Contaminants at the Air/Aqueous and Biological Soft Interfaces
Emerging Environmental Contaminants at the Air/Aqueous and Biological Soft Interfaces
复制标题
空气/水和生物软界面处的新兴环境污染物
DOI：
10.1039/d2va00081d
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Subir, Mahamud
中科院分区：
文献类型：
--
作者：
Dalla Pozza, Giada;Deardorff, Danielle;Subir, Mahamud
在地下水和地表水中检测微污染物，如具有内分泌干扰效力的药品和工业化学品，正在引起人们的关注。在水环境中，这些新出现的污染物(ECs)可以与各种表面和生物膜相互作用。这意味着，只要内皮细胞表现出足够的亲和力，这些表面就可以调节它们的命运和运输性质。了解与生物膜相互作用的类型也有助于破译它们对水生生物的影响。在这里，我们显示了选定的有机微污染物-氨氯地平(AMP)、卡马西平(CBZ)、β-雌二醇(β-ED)和4-丙基苯酚(4-PP)-表现出对空气/水界面的倾向。这些化合物与两性离子磷脂膜的相互作用也不同。水表面吸附自由能由大到小的顺序为：4-PP<；AMP<；β-ed∼CBZ。在所研究的四种化合物中，4-PP对磷脂膜的破坏程度最大。我们的结果表明，与水面和生物膜的相互作用程度取决于这些微污染物的化学性质。这项基础性研究强调了界面化学对天然水域中新出现的污染物的去向和传输的重要性。
Detection of micropollutants, such as pharmaceuticals and industrial chemicals with endocrine disrupting potency, in ground and surface waters is of emerging concern. Within the aquatic environment, these emerging contaminants (ECs) can interact with various surfaces and biological membranes. The implication is that, provided the ECs exhibit sufficient affinity, these surfaces can modulate their fate and transport properties. Knowledge of the types of interactions with biomembranes can also help decipher their impact on aquatic organisms. Here, we show that selected organic micropollutants – amlodipine (AMP), carbamazepine (CBZ), β-estradiol (β-ED), and 4-propylphenol (4-PP) – exhibit proclivity for the air/aqueous interface. These compounds also interact differently with a zwitterionic phospholipid membrane. The adsorption free energy for the water surface, in the order of increasing affinity, is as follows: 4-PP < AMP < β-ED ∼ CBZ. Of the four compounds studied, 4-PP has the greatest extent of disruption of the phospholipid membrane. Our results suggest that the extent of interaction with the water surface and biological membrane is dependent upon the chemical nature of these micropollutants. This fundamental study highlights the importance of interfacial chemistry on the fate and transport of emerging contaminants in natural waters.
影响因子：
56.9
作者：
M. Subir;Y. Rao
通讯作者：
Y. Rao