Genetic mapping of the p47 (L.3.2) mutation in Drosophilamelanogaster.
Genetic mapping of the p47 (L.3.2) mutation in Drosophilamelanogaster.
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DOI：
10.17912/micropub.biology.000783
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发表时间：
2023
影响因子：
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通讯作者：
Kagey, Jacob D
中科院分区：
文献类型：
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作者：
Cordes, Chloe N;Gouge, Melissa M;Morgan, Hannah;Porter, Carah;Siders, Jamie;Bacab, Erica;Barin, Briana;Becerra, Ixel A;Castillo, Jose;Church, Jared;Condo-Hicks, Shaunacee;Conroy, Kattleya J;Curbelo-Navarro, Isbel;DePrest, Benjamin J;Eady, Adrienne;Edmead, TyMahni;Farouk, Verena;Flores-Torres, Angelica;Girmai, Michael;Gutierrez Navarro, Cynthia I;Guzman, Stan;Harris, Alexis B;Healy, Karin;Jaafar, Alina;Khadr, Abraham;Kiboi, Melissa N;Korte, Stephanie N;Lopez, Celia;Mahdi, Hyder;Mendoza Avalos, Jennifer;Miranda, Kathy;Patel, Dipti;Lopez, Celia;Mahdi, Hyder;Mendoza Avalos, Jennifer;Miranda, Kathy;Patel, Dipti;Patel, Rishi;Pechulis, Sydney;Plachta, Victoria;Rhodes, Kamryn;Sandoval, Andrea M;Thomas, Caila;Valadez-Mendoza, Joselyn A;Vora, Hannah;Yousif, Jonathan;Bieser, Kayla L;Kagey, Jacob D
以EMS为基础的正向遗传筛查是在细胞凋零背景下进行的，以确定有助于调节果蝇细胞生长的遗传异常。目前的工作绘制了已识别的突变体之一L.3.2的基因组位置。通过苍蝇治愈联盟进行的遗传杂交确定了L.3.2突变的基因座是染色体2R上的P47。
An EMS-based forward genetic screen was conducted in an apoptotic null background to identify genetic aberrations that contribute to regulation of cell growth in Drosophila melanogaster . The current work maps the genomic location of one of the identified mutants, L.3.2 . Genetic crosses conducted through the Fly-CURE consortium determined that the gene locus for the L.3.2 mutation is p47 on chromosome 2R.