The Danish National Diabetes Register: trends in incidence, prevalence and mortality
The Danish National Diabetes Register: trends in incidence, prevalence and mortality
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DOI：
10.1007/s00125-008-1156-z
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发表时间：
2008-12-01
期刊：
影响因子：
8.2
通讯作者：
Borch-Johnsen, K.
中科院分区：
文献类型：
--
作者：
Carstensen, B.;Kristensen, J. K.;Borch-Johnsen, K.
这项研究的目的是描述丹麦糖尿病发病率、患病率和死亡率的趋势。国家卫生委员会的医疗登记被用来编制丹麦人口(540万人)中糖尿病患者的登记。计算了特定年龄和性别的患病率、发病率、死亡率和相对于非糖尿病人口的标准化死亡率。登记册包含约360,000名糖尿病患者的记录；截至2007年1月1日，有230,000人活着，相当于总患病率为4.2%。患病率以每年6%的速度增长。2004年，40岁的发病率为1.8/10万，70岁的发病率为10.0/10万。2004年前发病率以每年5%的速度增长，之后趋于稳定。糖尿病人群的死亡率每年下降4%，而非糖尿病人群的死亡率每年下降2%。在列入登记册后的头3年里，死亡率下降了40%。标准化死亡率随着年龄的增长而下降，男性和女性的标准死亡率从50岁的4.0下降到70岁的2.5，85岁的略低于2。标准化死亡率每历年下降1%。糖尿病的终生风险为30%。丹麦的糖尿病患病率在1995-2006年间上升，但糖尿病患者的死亡率下降速度快于非糖尿病人群。在列入登记册后，死亡率立即显著下降。在过去的几年里，发病率有下降的趋势，但应该谨慎看待这一发现。
The aim of the study was to describe trends in the incidence rate, prevalence and mortality rate for diabetes in Denmark.Healthcare registers at the National Board of Health were used to compile a register of diabetic patients in the Danish population (5.4 million people). Age- and sex-specific prevalence, incidence rates, mortality rates and standardised mortality ratios relative to the non-diabetic part of the population were calculated.The register contains records for about 360,000 persons with diabetes; 230,000 were alive at 1 January 2007, corresponding to an overall prevalence of 4.2%. The prevalence increased by 6% per year. In 2004 the incidence rates were 1.8 per 100,000 at age 40 years and 10.0 per 100,000 at age 70 years. The incidence rate increased 5% per year before 2004 and then stabilised. The mortality rate in the diabetic population decreased 4% per year, compared with 2% per year in the non-diabetic part of the population. The mortality rate decreased 40% during the first 3 years after inclusion in the register. The standardised mortality ratio decreased with age, from 4.0 at age 50 years to 2.5 at age 70 years and just under 2 at age 85 years, identically for men and women. The standardised mortality ratio decreased 1% per calendar year. The lifetime risk of diabetes was 30%.The prevalence of diabetes in Denmark rose in 1995-2006, but the mortality rate in diabetic patients decreased faster than that of the non-diabetic population. The mortality rate decreased markedly just after inclusion in the register. Incidence rates have shown a tendency to decrease during the last few years, but this finding should be viewed with caution.