Quantifying effects of retinal illuminance on frequency doubling perimetry.
Quantifying effects of retinal illuminance on frequency doubling perimetry.
复制标题
量化视网膜照度对倍频视野检查的影响。
DOI：
10.1167/iovs.04-0264
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发表时间：
2005
影响因子：
4.4
通讯作者：
Fischer,SusanE
中科院分区：
文献类型：
--
作者：
Swanson,WilliamH;Dul,MitchellW;Fischer,SusanE
目的。测量和量化视网膜照度变化对倍频技术（FDT）视界的影响。采用蔡司-汉弗莱/韦尔奇-阿林FDT周界和阈值N-30策略。研究1，量化适应：对11名受试者（24-46岁）的11只眼睛进行自然瞳孔测试，并在瞳孔稳定扩张后，在受试者眼前使用中性密度滤光片（0.0、0.6、1.2、1.6 log unit）进行重新测试。研究二，照度降低的预测效果：对17名受试者（26-61岁）的17只眼进行自然瞳孔测试，并在瞳孔稳定缩小后重新测试（用红外相机评估）。定量适应模型与研究1的结果吻合；研究2结果采用平均适应参数预测变化。研究1：在1.6 log单位的视网膜照度范围内，平均缺陷（MD）降低了10 dB；所有被试的模型拟合率为r 2 ~ 0 95%。研究2:MD变化（ΔMD）范围从−7.3 dB到+ 0.8 dB。研究1的平均适应参数占ΔMD方差的69% (P< 0.0005)，模型的准确性与ΔMD的大小无关（r 2< 1%， P> 0.75）。结果证实了先前的发现，FDT视距可以显著影响视网膜照度的变化。定量适应模型的应用为估计瞳孔直径和透镜密度对FDT视距的影响提供了指导。
purpose. To measure and quantify effects of variation in retinal illuminance on frequency doubling technology (FDT) perimetry.methods. A Zeiss-Humphrey/Welch Allyn FDT perimeter was used with the threshold N-30 strategy. Study 1, quantifying adaptation: 11 eyes of 11 subjects (24–46 years old) were tested with natural pupils, and then retested after stable pupillary dilation with neutral density filters of 0.0, 0.6, 1.2, and 1.6 log unit in front of the subject’s eye. Study 2, predicting effect of reduced illuminance: 17 eyes of 17 subjects (26–61 years old) were tested with natural pupils, and then retested after stable pupillary miosis (assessed with an infrared camera). A quantitative adaptation model was fit to results of Study 1; the mean adaptation parameter was used to predict change in Study 2.results. Study 1: Mean defect (MD) decreased by 10 dB over a 1.6 log unit range of retinal illuminances; model fits for all subjects had r 2> 95%. Study 2: Change in MD (ΔMD) ranged from− 7.3 dB to+ 0.8 dB. The mean adaptation parameter from Study 1 accounted for 69% of the variance in ΔMD (P< 0.0005), and accuracy of the model was independent of the magnitude of ΔMD (r 2< 1%, P> 0.75).conclusions. The results confirmed previous findings that FDT perimetry can be dramatically affected by variations in retinal illuminance. Application of a quantitative adaptation model provided guidelines for estimating effects of pupil diameter and lens density on FDT perimetry.