CORE TEMPERATURE IN FEMALE RAT - EFFECT OF OVARIECTOMY AND INDUCTION OF PSEUDOPREGNANCY
CORE TEMPERATURE IN FEMALE RAT - EFFECT OF OVARIECTOMY AND INDUCTION OF PSEUDOPREGNANCY
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DOI：
10.1152/ajplegacy.1976.231.2.361
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发表时间：
1976-01-01
影响因子：
--
通讯作者：
SPENCER, F
中科院分区：
文献类型：
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作者：
YOCHIM, JM;SPENCER, F
在发情周期中，大鼠核心体温的夜间峰值在排卵夜（2300-0200 h，发情前期-发情期）最高，在前一夜（发情间期2-发情前期）最低。不太戏剧性的昼夜第二高峰，缺席只在发情期，发生在3-4小时后，发病的日光。诱导假发情后，平均体温下降，但两个每日峰值持续到第1次黄体后发情，此时第二个峰值再次短暂消失。卵巢切除术降低了平均核心温度，并消除了所有的次要峰。相比之下，在假孕期间去势并没有消除第二峰。当周期性大鼠性腺切除（消除次级节律），有可能通过刺激子宫颈（好像诱导假性孕）重新建立这种节律。然而，在暴露于黑暗中的动物中（这也消除了次级节律），通过颈部刺激进行再诱导是无效的。第二峰的完整性，虽然依赖于光周期，但受到神经内分泌反射弧的影响。
Nocturnal peaks in core body temperature of rats during the estrous cycle were highest during the night of ovulation (2300-0200 h, proestrus-estrus) and lowest during the night before (diestrus 2-proestrus). Less dramatic diurnal secondary peaks, absent only during estrus, occurred 3-4 h after the onset of daylight. After induction of pseudopregnancy, mean temperature declined, but both daily peaks persisted until the 1st postluteal estrus, when the secondary peak was again absent transiently. Ovariectomy reduced mean core temperature and abolished all secondary peaks. In contrast, castration during pseudopregnancy did not abolish the secondary peaks. When cyclic rats were gonadectomized (abolishing the secondary rhythm) it was possible to reestablish this rhythm by stimulating the uterine cervix (as if to induce pseudopregnancy). However, in animals exposed to darkness (which also abolishes the secondary rhythm) reinduction by cervical stimulation was ineffective. The integrity of the secondary peak, though dependent on photoperiod, nevertheless was influenced by a neuroendocrine reflex arc.