Inaccurate Glucose Sensor Values After Hydroxyurea Administration

Inaccurate Glucose Sensor Values After Hydroxyurea Administration
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DOI:
10.1089/dia.2020.0490
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发表时间:
2020-12-30
影响因子:
5.4
通讯作者:
Elder, Deborah A.
Elder, Deborah A.
中科院分区:
医学3区
文献类型:
--
作者:
Tellez, Siobhan E.;Hornung, Lindsey N.;Elder, Deborah A.

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目的:为了评估的程度,持续时间,平均绝对相对差异(MARD),和误差分析的不一致值每连续血糖监测(CGM)系统后hydroxyurea(HU)administration.Research设计和方法:住院患者血糖仪和CGM数据从16个全胰腺切除术/胰岛自体移植患者使用Dexcom专业G4和12名患者使用Dexcom G6进行了分析后,每天服用HU。HU给药的时间和中位数为9.5天的传感器和血糖仪值进行了评估perpatient.Results:一个大的积极的传感器读数升高后确定HU给药。血糖仪和探头读数之间的最大差异发生在HU给药后0.5-2 h [G4(平均值3.0 mmol/L,中位数2.4 mmol/L,MARD 55%),G6(平均值4.2 mmol/L,中位数4.6 mmol/L,MARD 91%)]。矛盾在于
Objective: To assess the degree, duration, mean absolute relative difference (MARD), and error analysis of discrepant values per continuous glucose monitoring (CGM) systems after hydroxyurea (HU) administration.Research Design and Methods: Inpatient glucometer and CGM data from 16 total pancreatectomy/islet autotransplantation patients using Dexcom Professional G4 and 12 patients using Dexcom G6 were analyzed after daily dosing with HU. Timing of HU dosing and median of 9.5 days of sensor and glucometer values were assessed per patient.Results: A large positive elevation of sensor readings was identified after HU dosing. The greatest discrepancy between glucometer and sensor readings occurred 0.5-2 h after HU administration [G4 (mean 3.0 mmol/L, median 2.4 mmol/L, MARD 55%), G6 (mean 4.2 mmol/L, median 4.6 mmol/L, MARD 91%)]. The discrepancy was