Inaccurate Glucose Sensor Values After Hydroxyurea Administration
Inaccurate Glucose Sensor Values After Hydroxyurea Administration
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DOI:
10.1089/dia.2020.0490
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发表时间:
2020-12-30
影响因子:
5.4
通讯作者:
Elder, Deborah A.
中科院分区:
文献类型:
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作者:
Tellez, Siobhan E.;Hornung, Lindsey N.;Elder, Deborah A.
Objective: To assess the degree, duration, mean absolute relative difference (MARD), and error analysis of discrepant values per continuous glucose monitoring (CGM) systems after hydroxyurea (HU) administration.Research Design and Methods: Inpatient glucometer and CGM data from 16 total pancreatectomy/islet autotransplantation patients using Dexcom Professional G4 and 12 patients using Dexcom G6 were analyzed after daily dosing with HU. Timing of HU dosing and median of 9.5 days of sensor and glucometer values were assessed per patient.Results: A large positive elevation of sensor readings was identified after HU dosing. The greatest discrepancy between glucometer and sensor readings occurred 0.5-2 h after HU administration [G4 (mean 3.0 mmol/L, median 2.4 mmol/L, MARD 55%), G6 (mean 4.2 mmol/L, median 4.6 mmol/L, MARD 91%)]. The discrepancy was