Thymic mimicry: The art of imitation.
Thymic mimicry: The art of imitation.
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DOI:
10.1084/jem.20231010
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发表时间:
2023-10-02
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--
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Michelson and colleagues continue to advance our understanding of self-antigen representation by medullary thymic epithelial cells, identifying a new role for Hnf4γ in the regulation of thymic mimetic cells as well as their peripheral counterparts. Display of tissue self-antigens within the thymus is critical for the regulation of self-reactive T cells. In this issue of JEM, Michelson et al. (2023. J. Exp. Med. https://doi.org/10.1084/jem.20230461) continue to advance our understanding of self-antigen representation by medullary thymic epithelial cells, identifying a new role for Hnf4γ in the regulation of thymic mimetic cells as well as their peripheral counterparts.
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影响因子:
30.5
作者:
Brennecke P;Reyes A;Pinto S;Rattay K;Nguyen M;Küchler R;Huber W;Kyewski B;Steinmetz LM
通讯作者:
Steinmetz LM
影响因子:
16.6
作者:
Bautista JL;Cramer NT;Miller CN;Chavez J;Berrios DI;Byrnes LE;Germino J;Ntranos V;Sneddon JB;Burt TD;Gardner JM;Ye CJ;Anderson MS;Parent AV
通讯作者:
Parent AV
影响因子:
56.9
作者:
Anderson, MS;Venanzi, ES;Mathis, D
通讯作者:
Mathis, D
影响因子:
30.5
作者:
Derbinski, J;Schulte, A;Klein, L
通讯作者:
Klein, L
影响因子:
7.7
作者:
Wells KL;Miller CN;Gschwind AR;Wei W;Phipps JD;Anderson MS;Steinmetz LM
通讯作者:
Steinmetz LM