A (carbonmonoxy)heme complex with a weak proximal bond. Molecular stereochemistry of carbonyl(deuteroporphinato)(tetrahydrofuran)iron(II).
A (carbonmonoxy)heme complex with a weak proximal bond. Molecular stereochemistry of carbonyl(deuteroporphinato)(tetrahydrofuran)iron(II).
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具有弱近端键的（碳单氧基）血红素复合物。
DOI：
10.1021/bi00515a054
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发表时间：
1981
期刊：
影响因子：
2.9
通讯作者：
Reed,CA
中科院分区：
文献类型：
--
作者：
Scheidt,WR;Haller,KJ;Fons,M;Mashiko,T;Reed,CA
W. Robert Scheldt，* Kenneth J. Haller，M. Fons，ToshioMashiko和Christopher A. Reed* 摘要：本文报道了一种六配位（碳单氧基）（卟啉）铁（Ⅱ）-碳酰（次卟啉）（四氢呋喃）铁（Ⅱ）的合成和结构表征。选择四氢呋喃作为第六配体代表了可能的最弱场和最弱结合配体之一，并导致CO与血红素的键合比通常更强。Fe-C（CO）键距为1.706 π，异常短。低自旋配合物中的Fe-O（THF）键距为2.127 π。Fe-C-0和O-Fe-C基团是必不可少的。强场配体一氧化碳的结合在血红素蛋白和卟啉物种的研究中经常被利用。这些研究特别集中于探索血红素结合位点的性质以及评价顺式和反式效应（Caughey等人，1972; Buchler等人，1978年）。
W. Robert Scheldt,* Kenneth J. Haller, M. Fons, ToshioMashiko, and Christopher A. Reed* abstract: The synthesis and structural characterization of a six-coordinate (carbonmonoxy)(porphyrin) iron (II), car-bonyl (deuteroporphinato)(tetrahydrofuran) iron (II), is de-scribed. The choice of tetrahydrofuran as the sixth ligand represents one of the weakest field and weakest binding ligands possible and leads to stronger than usual bonding of CO to the heme. The Fe-C (CO) bond distance is 1.706 Á, unusually short. The Fe-O (THF) bond distance in the low-spin complex is 2.127 Á. The Fe-C-0 and O-Fe-C groups are essentiallyBinding of the strong-field ligand carbon monoxide has been frequently exploited instudies of hemoproteins and porphyrin species. These studies have focused particularly on exploring the nature of the heme binding site and the evaluation of cis and trans effects (Caughey et al., 1972; Buchler et al., 1978).