Predicting optical effects of tear film break up on retinal image quality using the Shack-Hartmann aberrometer and computational optical modeling.

Predicting optical effects of tear film break up on retinal image quality using the Shack-Hartmann aberrometer and computational optical modeling.
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使用 Shack-Hartmann 像差计和计算光学模型预测泪膜破裂对视网膜图像质量的光学影响。

DOI:
10.1007/978-1-4615-0717-8_160
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发表时间:
2002
影响因子:
--
通讯作者:
Begley,CarolynG
Begley,CarolynG
中科院分区:
医学4区
文献类型:
--
作者:
Himebaugh,NikoleL;Thibos,LarryN;Bradley,Arthur;Wilson,Graeme;Begley,CarolynG

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角膜前泪膜是眼睛的最前部折射表面。从空气到眼泪折射率的巨大变化使其成为具有最大光功率的表面。因此,不均匀厚度的泪膜可能对眼睛的光学质量产生重大影响。1.2许多临床研究表明,在眨眼之间的时间段内,泪膜不稳定,并且在眼睛表面上不保持均匀。相反,它似乎局部破坏,这是一种被临床医生称为泪膜破裂的现象,导致泪膜厚度不均匀。尽管泪膜破裂通常不被认为是一种光学现象,但有实验证据支持泪膜厚度局部变化影响眼睛光学质量的假设。3.5这些实验研究的结论得到了干眼症患者和隐形透镜佩戴者报告的“模糊“、6.7“干扰“、8.9和“波动”视力以及视力下降的临床证据的支持。
The pre-corneal tear film is the most anterior refracting surface of the eye. The large change in refractive index from air to tears makes it the surface with the greatest optical power. Therefore, a tear film of non-uniform thickness can potentially have a significant impact on the optical quality of the eye.1.2Many clinical studies have shown that, during periods between blinks, the tear film is not stable and does not remain uniform on the surface of the eye. Instead, it appears to disrupt locally, a phenomenon termed tear film breakup by clinicians, resulting in a tear film which is non-uniform in thickness. Although tear breakup is not usually regarded as an optical phenomenon, there is experimental evidence supporting the hypothesis that local changes in tear film thickness impact the optical quality of the eye.3.5The conclusions from these experimental studies are supported by clinical evidence of “blurry,”6.7“disturbed,”8.9and “fluctuating” vision, and reduced visual acuity reported by dry eye patients and contact lens wearers.
血管造影隐秘的组织学证实的脑血管畸形。
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