Management of Acute Promyelocytic Leukemia

Management of Acute Promyelocytic Leukemia
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急性早幼粒细胞白血病的治疗

DOI:
10.1007/978-3-030-72676-8_8
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发表时间:
2021
期刊:
Acute Myeloid Leukemia
影响因子:
--
通讯作者:
U. Platzbecker
U. Platzbecker
中科院分区:
--
文献类型:
--
作者:
S. Kayser;U. Platzbecker

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随着全反式维甲酸(ATRA)和三氧化二砷(ATO)的引入,急性早幼粒细胞白血病(APL)已从一种有害的人类恶性疾病发展成为最可治愈的恶性疾病之一。特别是,ATO/ATRA的无化疗联合方案已被证明在新发APL中比基于化疗的治疗更有利,并已成为非高危APL患者的标准一线治疗。本文就APL的诊断方法、治疗及并发症的处理进行讨论。
With the introduction of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) acute promyelocytic leukemia (APL) has become from a detrimental to one of the most curable malignant diseases in humans. In particular, the chemotherapy-free combination regimen with ATO/ATRA has been proven to be advantageous compared to chemotherapy-based treatments in de novo APL and has become standard first-line therapy in non-high-risk APL patients. We here discuss the diagnostic approach, treatment as well as management of complications of patients with APL.
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发表时间: 1994-12-01
期刊: BLOOD
影响因子: 20.3
作者:
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期刊: BLOOD
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