The role of alcohol in cocaine dependence.
The role of alcohol in cocaine dependence.
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酒精在可卡因依赖中的作用。
DOI：
10.1007/978-1-4899-1648-8_1
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Anglin,MD
中科院分区：
文献类型：
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作者：
Khalsa,H;Paredes,A;Anglin,MD
使用来自作者的研究数据和文献的信息来检查酒精和可卡因使用模式之间的关系。在西洛杉矶的一家退伍军人管理局医院寻求可卡因依赖治疗的男性中，过度饮酒非常普遍。50%的人符合DSM-III-R酒精依赖标准。比较单纯可卡因依赖与可卡因和酒精依赖患者的药物相关行为。可卡因成瘾的进展在这两组中没有显着差异。然而，对可卡因和酒精有依赖的患者更有可能是其他滥用药物的使用者。在心理社会行为方面，两组在成瘾生涯的重要时期都保持了就业和稳定的人际关系。在药物治疗一年后，两个子样本在可卡因和酒精使用以及社会适应方面都有显着改善。研究的影响和可能性，这两个依赖条件可能会分享神经行为强化机制进行了讨论。
The relationships between the patterns of alcohol and cocaine use are examined using information derived from the authors’ research data and from the literature. Excessive alcohol drinking was very prevalent among males seeking treatment for cocaine dependence at a Veterans Administration hospital in West Los Angeles. Fifty percent met DSM-III-R criteria for alcohol dependence. The drug-related behaviors of patients with the diagnosis of dependence on cocaine only were compared with those of patients dependent on cocaine and alcohol. The progression of the cocaine addiction was not significantly different in those two groups. However, patients with dependence on cocaine and alcohol were more likely to be users of other drugs of abuse. Concerning psychosocial behaviors, both groups maintained employment and stable interpersonal relationships throughout significant periods of their addictive career. One year after drug treatment, both subsamples showed significant improvement in terms of cocaine and alcohol use and social adjustment. Research implications and the possibility that both dependent conditions may share neurobehavioral reinforcing mechanisms are discussed.