Microbiological Profile in Periodontitis and Peri-Implantitis: A Systematic Review.
Microbiological Profile in Periodontitis and Peri-Implantitis: A Systematic Review.
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DOI：
10.1615/jlongtermeffmedimplants.2022043121
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发表时间：
2022-01-01
影响因子：
--
通讯作者：
Varghese, Sheeja S
中科院分区：
文献类型：
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作者：
Rajasekar, Arvina;Varghese, Sheeja S
了解种植体周围生物膜的微生物组成有助于发现有针对性的治疗策略，改善种植体周围炎管理的结果。然而，患病牙周和种植体周围沟中的细菌分布仍不清楚。本系统综述旨在根据现有文献证据分析患病牙周沟和种植体周围沟之间的微生物相似性和差异。在PubMed、Google Scholar和科克伦等电子数据库中进行了全面检索，并采用合格性标准进行了手动检索。经过全面审查，选择了评价从患牙周病和种植体周围沟的患者获得的菌斑样本中获得的微生物组成的研究。所选的8项研究评价了牙周炎和种植体周围炎的微生物谱差异。五项研究发现，患病牙周和种植体周围沟之间的微生物分布存在统计学显著差异，而在一项研究中，未观察到炎症性种植体周围和牙周部位的微生物学变化。在两项原位研究中的一项中，种植体周围炎的转录水平和核心物种的结构不同，而另一项原位研究发现，两种疾病的基于16S rRNA的细菌谱不同，而功能基因、分类学和毒力因子mRNA谱相同。根据现有的研究，观察到患病牙周和种植体周围沟的生物膜组成的显着差异。因此，牙周炎和种植体周围炎具有不同的微生物特征。
Understanding the microbiological makeup of peri-implant biofilm could contribute to the discovery of focused treatment strategies, improving the outcome of peri-implantitis management. However, the bacterial profile in diseased periodontal and peri-implant sulci is still unclear. This systematic review aims to analyze the microbiological similarities and differences between diseased periodontal and peri-implant sulci based on the available literature evidence. A thorough search was conducted in electronic databases such as PubMed, Google Scholar, and Cochrane, as well as a manual search employing the eligibility criteria. After a thorough review, studies evaluating the microbial composition acquired from plaque samples obtained from patients with diseased periodontal and peri-implant sulci were chosen. The selected 8 studies evaluated the differences in microbial profile in periodontitis and peri-implantitis. Five studies found a statistically significant variation in the microbial profile between diseased periodontal and peri-implant sulci, while in one study, no changes in the microbiology of inflammatory peri-implant and periodontal sites were observed. In one of the two in situ studies, the structure of the transcription level and core species was different in peri-implantitis, whereas the other in situ study found that the 16S rRNA-based bacterial profile of both the diseases were different, while the functional genes, taxonomic, and virulence factor mRNA profiles were identical. According to existing studies, significant differences in the biofilm composition of diseased periodontal and peri-implant sulci were observed. Therefore, periodontitis and peri-implantitis have diverse microbial characteristics.