Electrical Impedance Myography for Assessing Paraspinal Muscles of Patients with Low Back Pain.
Electrical Impedance Myography for Assessing Paraspinal Muscles of Patients with Low Back Pain.
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DOI：
10.2478/joeb-2019-0015
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发表时间：
2019-01
影响因子：
--
通讯作者：
Keel J
中科院分区：
文献类型：
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作者：
Wang Y;Freedman L;Buck M;Bohorquez J;Rutkove SB;Keel J
本研究的目的是确定电阻抗肌电图（EIM）评估腰骶椎旁肌（LPM）的条件下背痛（LBP）患者的潜在价值。用于评估LPM状况的标准方法，例如磁共振成像，是不方便且昂贵的。电阻抗肌电图（EIM）是一种可以在床边快速进行的技术。在接受筛选病史和检查后，使用mView EIM器械（Myolex，Inc，Boston）对受试者进行研究。双侧LPM各测量三次，每侧最接近的两组测量值取平均值。数据分析包括健康受试者和背痛患者之间的非参数两组比较、受试者工作曲线分析以及与年龄和体重指数的相关性分析。共入组86名健康个体（中位年龄（四分位距）（IQR），45.5岁（30.3-56.0岁），42名男性，44名女性）和47名LBP（中位年龄51.0岁（39.5-57.5）岁，21名男性，26名女性）。LBP患者的中位EIM 100 kHz相位较低（9.3°（IQR 8.4°-10.6°）vs 11.4°（IQR 9.4°-13.0°），p = 0.0007）。所有三个EIM变量（例如，中位100 kHz相位为0.15（LBP患者的IQR为0.07-0.31，健康个体为0.09（IQR为0.04-0.17））。发现100 kHz EIM相位和电抗之间存在显著相关性（Rspearman=-0.46，P=0.0002和Rspearman=-0.440，P=0.0003），但电阻不相关。这项研究提供了早期的证据支持，EIM有可能作为一个有用的工具，用于评估LPMs的条件。
The objective of this study was to determine the potential value of electrical impedance myography (EIM) for assessing lumbosacral paraspinal muscle (LPM) condition in lower back pain (LBP) patients. Standard methods for assessing the condition of LPMs, such as magnetic resonance imaging, are inconvenient and expensive. One tool that could be useful for this purpose is electrical impedance myography (EIM) a technique that can be performed rapidly at the bedside. After undergoing a screening history and examination, subjects were studied with the mView EIM device (Myolex, Inc, Boston). Bilateral LPMs were measured three times each and the two closest sets of measurements averaged on each side. Data analysis included non-parametric two-group comparisons between healthy subjects and back pain patients, receiver-operating curve analyses, and correlation analyses to age and body mass index. A total of 86 healthy individuals (median age (interquartile range) (IQR), 45.5 years (30.3–56.0 years), 42 men, 44 women) and 47 LBP (median age 51.0 year (39.5–57.5) years, 21 men, 26 women) were enrolled. Median EIM 100kHz phase was lower in the LBP patients (9.3°(IQR 8.4°–10.6°) versus 11.4°(IQR 9.4°–13.0°), p = 0.0007). Significantly increased normalized side-to-side differences were present for all three EIM variables (e.g., median 100 kHz phase 0.15 (IQR 0.07–0.31 in LBP patients versus 0.09 (IQR 0.04–0.17) in healthy individuals). A significant correlation between 100 kHz EIM phase and reactance was found with age (Rspearman=−0.46, P=0.0002 and Rspearman=−0.440, P=0.0003) but not for resistance. This study provides early evidence supporting that EIM has the potential to serve as a useful tool for evaluating the condition of LPMs.