Effect of selection for behavior on pituitary-adrenal axis and proopiomelanocortin gene expression in silver foxes (Vulpes vulpes)
Effect of selection for behavior on pituitary-adrenal axis and proopiomelanocortin gene expression in silver foxes (Vulpes vulpes)
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DOI：
10.1016/j.physbeh.2004.04.062
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发表时间：
2004-09-15
影响因子：
2.9
通讯作者：
Trut, LN
中科院分区：
文献类型：
--
作者：
Gulevich, RG;Oskina, IN;Trut, LN
研究了来自商业种群（农场饲养的或为控制行为而饲养的）和来自选择用于驯服行为和增强对人类攻击性的种群的银狐。评估血浆皮质醇和促肾上腺皮质激素（ACTH）水平、垂体ACTH水平、垂体前叶POW基因表达和下丘脑促肾上腺皮质激素释放因子（CRF）基因表达。结果表明，从驯服行为组的男性有较低的血浆皮质醇和促肾上腺皮质激素水平和POW基因表达在垂体前叶响应捕获和处理相比，与雌激素。来自攻击行为组的狐狸也有较低的POW表达，尽管血浆皮质醇和ACTH水平与雌狐相同。三组动物垂体中的促肾上腺皮质激素水平和下丘脑中的CRY表达没有显着变化。(C)2004年爱思唯尔公司All rights reserved.
Silver foxes from a commercial population (farm bred or unselected for behavior control) and from populations selected for tame behavior and enhanced aggressiveness towards man have been investigated. Plasma cortisol and adrenocorticotropic hormone (ACTH) levels, pituitary ACTH levels, POW gene expression in the anterior pituitary, and corticotropin-releasing factor (CRF) gene expression in the hypothalamus were assessed. The results indicate that the males from the tame-behavior group have lower plasma cortisol and ACTH levels and POW gene expression in the anterior pituitary in response to capture and handling in comparison with unselected ones. Foxes from the aggressive behavior group also have lower POW expression, although plasma cortisol and ACTH levels remain the same as in unselected ones. The three groups of animals show no significant changes in the ACTH level in the pituitary and CRY expression in the hypothalamus. (C) 2004 Elsevier Inc. All rights reserved.