Comparison of Design Approaches for Low-Cost Sampling Mechanisms in Open-Source Chemical Instrumentation.
Comparison of Design Approaches for Low-Cost Sampling Mechanisms in Open-Source Chemical Instrumentation.
复制标题
开源化学仪器中低成本采样机制的设计方法比较。
DOI：
10.1016/j.ohx.2021.e00220
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发表时间：
2021
期刊：
影响因子：
2.2
通讯作者：
Grinias,JamesP
中科院分区：
文献类型：
--
作者：
Murray,Greggory;Bednarski,Samuel;Hall,Michael;Foster,SamuelW;Jin,SiJun;Davis,JoshuaJ;Xue,Wei;Constans,Eric;Grinias,JamesP
机器人定位系统用于各种化学仪器中，主要用于液体处理目的，例如小瓶或孔板的自动进样器。在这里，两种方法来设计的开源自动进样器定位系统与96孔板的描述和比较。第一个系统是一个类似于市场上许多低成本3D打印机的3轴设计，使用铝制框架和步进电机构建。另一个系统依赖于一系列3D打印部件，以实现基于选择性顺应性装配机器人臂（SCARA）设计原则的一系列连接臂的运动。完整的打印机设计文件，装配说明，软件和用户指南包括两个采样器。3轴系统的定位精度优于SCARA机构，这是由于更精细的电机控制，尽管材料成本略高。基于该方法的改进的精度，使用3轴自动进样器系统来证明从96孔板内的相邻威尔斯孔产生分段流动液滴流。
Robotic positioning systems are used in a variety of chemical instruments, primarily for liquid handling purposes, such as autosamplers from vials or well plates. Here, two approaches to the design of open-source autosampler positioning systems for use with 96-well plates are described and compared. The first system, a 3-axis design similar to many low-cost 3D printers that are available on the market, is constructed using an aluminum frame and stepper motors. The other system relies upon a series of 3D printed parts to achieve movement with a series of linker arms based on Selective Compliance Assembly Robot Arm (SCARA) design principles. Full printer design files, assembly instructions, software, and user directions are included for both samplers. The positioning precision of the 3-axis system is better than the SCARA mechanism due to finer motor control, albeit with a slightly higher cost of materials. Based on the improved precision of this approach, the 3-axis autosampler system was used to demonstrate the generation of a segmented flow droplet stream from adjacent wells within a 96-well plate.