Using Population Based Hospitalization Data to Monitor Increases in Conditions Causing Morbidity Among Persons Who Inject Drugs
Using Population Based Hospitalization Data to Monitor Increases in Conditions Causing Morbidity Among Persons Who Inject Drugs
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DOI：
10.1007/s10900-017-0458-9
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发表时间：
2018-06-01
影响因子：
5.9
通讯作者：
Asher, Alice
中科院分区：
文献类型：
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作者：
Collier, Melissa G.;Doshani, Mona;Asher, Alice
阿片类药物使用和注射毒品使用（IDU）的流行与美国艾滋病毒和病毒性肝炎感染以及吸毒过量死亡的增加有关。注射毒品者也有因注射吸毒者引入的皮肤微生物而引起严重感染的风险。我们检查了全国住院患者样本出院数据，以确定除HIV和病毒性肝炎外主要影响PWID的三种严重传染病相关疾病的趋势：感染性心内膜炎（IE）、中枢神经系统（CNS）脓肿和骨髓炎。我们发现，从2009年到2013年，年龄在39岁以上的人中，IE的主要住院出院诊断数量增加。在本研究期间，对于继发性诊断为B、C或D型肝炎病毒和物质相关疾病IE、CNS脓肿和骨髓炎的患者，这些诊断的住院率也增加。改善获得无菌注射设备的机会、改善关于注射吸毒者的教育和治疗药物使用障碍的政策可能有助于减少严重和往往致命的传染病对艾滋病感染者的影响。
Epidemics of opioid use and injection drug use (IDU) are associated with an increase in HIV and viral hepatitis infections and overdose deaths in the United States. Persons who inject drugs (PWID) are also at risk for serious infections caused by skin organisms introduced via IDU. We examined National Inpatient Sample hospital discharge data to determine trends in three serious infectious disease-associated conditions that primarily affect PWID in addition to HIV and viral hepatitis: infective endocarditis (IE), central nervous system (CNS) abscesses, and osteomyelitis. We found an increase in the number of primary hospitalization discharge diagnoses for IE among persons aged ae39 years from 2009 to 2013. Hospitalization rates for these diagnoses also increased over this study period for person with secondary diagnoses of hepatitis B, C, or D viruses and substance-related disorders for IE, CNS abscess and osteomyelitis. Policies that improve access to sterile injection equipment, improve education regarding IDU, and treatment for substance use disorder may help to reduce the impact of serious and often fatal infectious diseases among PWID.