DISTRIBUTION OF MAST-CELLS IN HUMAN DERMIS - DEVELOPMENT OF A MAPPING TECHNIQUE
DISTRIBUTION OF MAST-CELLS IN HUMAN DERMIS - DEVELOPMENT OF A MAPPING TECHNIQUE
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DOI：
10.1111/j.1365-2133.1979.tb08066.x
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发表时间：
1979-01-01
影响因子：
10.3
通讯作者：
EADY, RAJ
中科院分区：
文献类型：
--
作者：
COWEN, T;TRIGG, P;EADY, RAJ
建立了一种新的方法来确定肥大细胞在正常人皮肤中的分布。在真皮中不同深度的多个区域中测定群体密度。对同一肢体的两个区域进行了系统的研究。两者都具有相似大小和分布的肥大细胞群，最大密度紧接在真皮-表皮交界处下方，逐渐下降到真皮深层的最小密度。较小的次峰在真皮基部不太清楚。这些发现应提供基线数据，用于与正常皮肤的不同区域或临床疾病或实验条件下的相似区域中的肥大细胞群体大小和分布进行比较。
A new method was developed to define the distribution of mast cells in normal human skin. The population density was determined in a number of zones of different depth in the dermis. Two regions of the same limb were studied systematically. Both have mast cell populations of similar size and distribution, with a maximum density immediately below the dermo-epidermal junction, gradually falling to a minimum density in the deeper layers of the dermis. Small secondary peaks were less clearly defined at the base of the dermis. These findings should provide baseline data for comparisons with mast cell population size and distribution in different areas of normal skin, or in similar areas in clinical disorders or experimental conditions.