Molecular defects in the growth hormone-IGF axis.
Molecular defects in the growth hormone-IGF axis.
复制标题
生长激素-IGF 轴的分子缺陷。
DOI：
10.1007/bf02760700
复制
发表时间：
2005
影响因子：
4.3
通讯作者：
Menon,RamK
中科院分区：
文献类型：
--
作者：
Lee,Joyce;Menon,RamK
许多以前没有特征的儿童发育不良病例，即特发性矮小，现在可归因于GH-IGF-1轴的遗传缺陷。本文将提供的临床结果的概述与生长激素/胰岛素样生长因子-1轴的各种遗传缺陷的患者，重点是最近描述的症状。
Many previously uncharacterized cases of poor growth in children, i.e. idiopathic short stature, are now attributable to genetic defects in the GH-IGF-1 axis. This paper will provide an overview of the clinical findings of patients identified with various genetic defects of the GH/IGF-1 axis with an emphasis on the more recently described syndromes.