Predictors of outcome after temporal lobectomy for the treatment of intractable epilepsy
Predictors of outcome after temporal lobectomy for the treatment of intractable epilepsy
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DOI：
10.1212/01.wnl.0000219810.71010.9b
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发表时间：
2006-06-27
期刊：
影响因子：
9.9
通讯作者：
Luders, H. O.
中科院分区：
文献类型：
--
作者：
Jeha, L. E.;Najm, I. M.;Luders, H. O.
为了评估短期和长期癫痫发作自由度，作者回顾了371例接受前颞叶切除术治疗耐药癫痫的患者。平均随访时间为5.5年（1 ~ 14.1年）。53%的患者在10年内没有癫痫发作。作者确定了多种复发预测因素。术后6个月脑电图结果与癫痫复发的发生及严重程度相关，除停药后出现突破性发作外。
To assess short- and long-term seizure freedom, the authors reviewed 371 patients who underwent anterior temporal lobectomy to treat pharmacoresistant epilepsy. The mean follow-up duration was 5.5 years (range 1 to 14.1 years). Fifty-three percent of patients were seizure free at 10 years. The authors identified multiple predictors of recurrence. Results of EEG performed 6 months postoperatively correlated with occurrence and severity of seizure recurrence, in addition to breakthrough seizures with discontinuation of antiepileptic drugs.