Accuracy of real-time MR temperature mapping in the brain: A comparison of fast sequences
Accuracy of real-time MR temperature mapping in the brain: A comparison of fast sequences
复制标题
DOI：
10.1016/j.ejmp.2009.11.006
复制
发表时间：
2010-10-01
期刊：
影响因子：
--
通讯作者：
Schick, Fritz
中科院分区：
文献类型：
--
作者：
Kickhefel, A.;Roland, Joerg;Schick, Fritz
目的：在1.5T和3 T条件下，比较基于质子共振频率（PRF）方法的磁共振（MR）测温法（使用单次激发回波平面成像（ss EPI）序列）与标准序列梯度回波（GRE）和分段回波平面成像（seg EPI）在活体人脑中的表现。材料和方法：使用GRE、seg EPI和ss EPI序列在全身1.5T和31个临床系统上使用可比的采集参数对6名志愿者的大脑进行重复MR测温。在两种场强下，在12 min内测定三个序列在人体头部的相位稳定性和温度数据精度。一个离体猪骨骼肌模型被用来评估的ss EPI序列在加热过程中的温度精度的高强度聚焦超声（HIFU）。结果：在体内检查的大脑显示的平均温度精度为0.37摄氏度/0.39摄氏度/0.16摄氏度在3 T的GRE/seg EPI/ss EPI序列。在1.5T下，实现了0.58摄氏度/0.63摄氏度/0.21摄氏度的精度。在离体猪模型中，发现使用ss EPI和GRE序列获得的温度数据与温度偏差有很强的相关性
Purpose: To compare magnetic resonance (MR) thermometry based on the proton resonance frequency (PRF) method using a single shot echoplanar imaging (ss EPI) sequence to both of the standard sequences, gradient echo (GRE) and segmented echoplanar imaging (seg EPI) in the in vivo human brain, at 1.5T and 3T.Material and methods: Repetitive MR thermometry was performed on the brain of six volunteers using GRE, seg EPI, and ss EPI sequences on whole-body 1.5T and 31 clinical systems using comparable acquisition parameters. Phase stability and temperature data precision in the human head were determined over 12 min for the three sequences at both field strengths. An ex-vivo swine skeletal muscle model was used to evaluate temperature accuracy of the ss EPI sequence during heating by high intensity focused ultrasound (HIFU).Results: In-vivo examinations of brain revealed an average temperature precision of 0.37 degrees C/0.39 degrees C/0.16 degrees C at 3T for the GRE/seg EPI/ss EPI sequences. At 1.5T, a precision of 0.58 degrees C/0.63 degrees C/0.21 degrees C was achieved. In the ex-vivo swine model, a strong correlation of temperature data derived using ss EPI and GRE sequences was found with a temperature deviation