Withdrawal of immunosuppression in liver allograft recipients.

Withdrawal of immunosuppression in liver allograft recipients.
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同种异体肝移植受者停止免疫抑制。

DOI：
10.1002/lt.500040309
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发表时间：
1998
期刊：
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
影响因子：
--
通讯作者：
P. Mcmaster
P. Mcmaster
中科院分区：
--
文献类型：
--
作者：
R. Padbury;G. Toogood;P. Mcmaster

文献摘要

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减少肝移植受者免疫抑制长期副作用的策略包括在双或三联治疗方案中统一减少所有药物，选择性停用此类方案中的单个药物，以及完全停用所有长期免疫抑制。在预防移植物免疫损伤的同时，消除严重的心血管、感染和肿瘤并发症的最有效的临床方案尚不明确。
trategies to minimize the long-term side effectsof immunosuppression in liver transplant re-cipients have included the uniform reduction of allagents in double- or triple-therapy regimens, selec-tive discontinuation of individual agents of suchregimens, and the complete withdrawal of alllong-term immunosuppression. The most effectiveclinical protocol to eliminate the serious cardiovas-cular,infectious,andneoplasticcomplicationswhilepreventing immunologic graft damage is not yetapparent.