Irlen syndrome: systematic review and level of evidence analysis
Irlen syndrome: systematic review and level of evidence analysis
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DOI：
10.1590/0004-282x20190014
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发表时间：
2019-03-01
影响因子：
1.4
通讯作者：
Wajnsztejn, Rubens
中科院分区：
文献类型：
--
作者：
Miyasaka, Jordan Da Silva;Vieira, Raphael V. Gonzaga;Wajnsztejn, Rubens
背景：暗位敏感综合征，后来被称为Meares-Irlen综合征或简称Irlen综合征（IS），被描述为由于颜色匹配差和图形图像失真而导致阅读能力差的症状。患有这种综合症的人被认为阅读速度慢、效率低、理解力差、视觉疲劳。目前尚不清楚该疾病的病理生理是一个独立的实体还是阅读障碍谱系的一部分。尽管如此，人们还是建议使用镜片和彩色滤光片来缓解发光对比的影响，提高患者的阅读能力。然而，没有证据表明治疗有效。目的：探讨IS的病因、诊断及干预效果。方法：对IS的现有研究进行系统回顾，根据证据水平评估现有数据，重点关注诊断工具、建议的干预措施和相关结果。结果：各研究间数据异质性较高，缺乏IS存在及治疗效果的证据。结论：所描述的综合征及其治疗方法需要进一步的有力证据。
Background: Scotopic sensitivity syndrome, later called Meares-Irlen syndrome or simply Irlen syndrome (IS) has been described as symptoms of poor reading ability due to poor color matching and distorted graphic images. Individuals with this syndrome are considered slow, ineffective readers with low comprehension and visual fatigue. It is still uncertain whether the disease pathophysiology is an independent entity or part of the dyslexia spectrum. Nevertheless, treatments with lenses and colored filters have been proposed to alleviate the effect of the luminous contrast and improve patients' reading performance. However, no evidence of treatment effectiveness has been achieved. Objective: The aim of the present study was to obtain evidence about IS etiology, diagnosis and intervention efficacy. Methods: A systematic review was performed covering the available studies on IS, assessing the available data according to their level of evidence, focusing on diagnostic tools, proposed interventions and related outcomes. Results: The data showed high heterogeneity among studies, and lack of evidence on the existence of IS and treatment effectiveness. Conclusion: The syndrome as described, as well as its treatments, require further strong evidence.