Value of multiple sclerosis diagnostic criteria. 70 autopsy-confirmed cases.
Value of multiple sclerosis diagnostic criteria. 70 autopsy-confirmed cases.
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多发性硬化症诊断标准的价值。
DOI：
10.1001/archneur.1985.04060080026010
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发表时间：
1985
影响因子：
--
通讯作者：
F. Lhermitte
中科院分区：
文献类型：
--
作者：
G. Izquierdo;J. Hauw;O. Lyon‐Caen;R. Marteau;R. Escourolle;A. Buge;P. Castaigne;F. Lhermitte
我们通过对70例经病理证实的多发性硬化患者的临床资料的回顾研究，评价了最新、最常用的多发性硬化诊断标准的敏感性。对于每个病例，分别使用不同的标准来确定诊断日期。然后计算诊断延迟时间。当使用某些标准时，诊断的时间明显更早。在疾病的早期，这一点更加明显。我们还发现，无论采用什么标准，进行性多发性硬化症的确诊时间都晚于其他病程的患者。这只对单一标准有统计学意义。
We have evaluated the sensitivity of the most recent and most frequently used criteria for the diagnosis of definite multiple sclerosis by the retrospective study of the clinical files of 70 pathologically confirmed cases. For each case, the date of diagnosis was determined separately using different sets of criteria. The delay of diagnosis was then calculated. The diagnosis was made significantly earlier when certain criteria were used. This was more marked in the earlier years of the disease. We also found that cases of multiple sclerosis with progressive courses were diagnosed later than cases with other courses, whatever the criteria used. This was statistically significant only for a single criterion.