Information and communication theory in molecular biology
Information and communication theory in molecular biology
复制标题
分子生物学中的信息与通信理论
DOI:
10.1007/s00202-007-0062-6
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发表时间:
2007
影响因子:
1.8
通讯作者:
Jakob C. Mueller
中科院分区:
文献类型:
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作者:
P. Hanus;Bernhard Goebel;J. Dingel;J. Weindl;J. Zech;Z. Dawy;J. Hagenauer;Jakob C. Mueller
The DNA sequencing efforts of the past years together with rapid progress in sequencing technology have generated a huge amount of sequence data available in public molecular databases. This recent development makes it statistically feasible to apply universal concepts from Shannon’s information theory to problems in molecular biology, e.g to use mutual information for gene mapping and phylogenetic classification. Additionally, the genetic information in the cell is continuously subject to mutations. However, it has to be passed from generation to generation with high fidelity, raising the question of existence of error protection and correction mechanisms similar to those used in technical communication systems. Finally, better understanding of genetic information processing on the molecular level in the cell can be acquired by looking for parallels to well established models in communication theory, e.g. there exist analogies between gene expression and frame synchronization.
影响因子:
7
作者:
Siepel, A;Bejerano, G;Haussler, D
通讯作者:
Haussler, D
DOI:
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发表时间:
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期刊:
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影响因子:
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作者:
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