Determination of Serum Homocysteine and Hypersensitive C-reactive Protein and Their Correlation with Premature Coronary Heart Disease
Determination of Serum Homocysteine and Hypersensitive C-reactive Protein and Their Correlation with Premature Coronary Heart Disease
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DOI:
10.1532/hsf.2223
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发表时间:
2019-01-01
影响因子:
0.6
通讯作者:
Niu, Xiaohua
中科院分区:
文献类型:
--
作者:
Li, Songsen;Pan, Guangjie;Niu, Xiaohua
Background: This study aims to investigate the correlation between premature coronary heart disease (pCHD) and both serum homocysteine (Hcy) and hypersensitive C-reactive protein (hs-CRP).Methods: A total of 170 patients with pCHD were enrolled in this study from June 2014 to April 2016 (including 52 patients with stable angina pectoris [SAP], 70 patients with unstable angina pectoris [UAP], and 48 patients with acute myocardial infarction [AMI]), together with 105 healthy controls (CON) selected at the same period, to observe the changes of Hcy and hs-CRP in CHD patients and those with different types of CHD.Results: The levels of serum Hcy and hs-CRP in group pCHD were significantly higher than in group CON (P