Confirmation of Putative HIV-1 Group P in Cameroon
Confirmation of Putative HIV-1 Group P in Cameroon
复制标题
DOI：
10.1128/jvi.02005-10
复制
发表时间：
2011-02-01
影响因子：
5.4
通讯作者：
Brennan, Catherine A.
中科院分区：
文献类型：
--
作者：
Vallari, Ana;Holzmayer, Vera;Brennan, Catherine A.
我们报告的第二个人类免疫缺陷病毒（HIV）属于新的HIV 1型（HIV-1）P组谱系，是密切相关的猿免疫缺陷病毒在大猩猩中发现。在喀麦隆一名艾滋病毒血清反应阳性的男性住院患者中发现了这种病毒，证实P组病毒正在人类中传播。在喀麦隆收集的1 736份艾滋病毒血清阳性标本的筛查结果表明，艾滋病毒-1 P组感染很罕见，仅占艾滋病毒感染的0.06%。尽管P组很罕见，但它显示出适应人类的证据。
We report the second human immunodeficiency virus (HIV) belonging to the new HIV type 1 (HIV-1) group P lineage that is closely related to the simian immunodeficiency virus found in gorillas. This virus was identified in an HIV-seropositive male hospital patient in Cameroon, confirming that the group P virus is circulating in humans. Results from screening 1,736 HIV-seropositive specimens collected in Cameroon indicate that HIV-1 group P infections are rare, accounting for only 0.06% of HIV infections. Despite its rarity, group P shows evidence of adaptation to humans.