Progressive rural-urban disparity in acute stroke care

Progressive rural-urban disparity in acute stroke care
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DOI:
10.1212/wnl.0000000000003562
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发表时间:
2017-01-31
期刊:
影响因子:
9.9
通讯作者:
Willis, Allison W.
Willis, Allison W.
中科院分区:
医学1区
文献类型:
--
作者:
Gonzales, Sergio;Mullen, Michael T.;Willis, Allison W.

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目的:探讨急性缺血性卒中(AIS)患者组织纤溶酶原激活剂(tPA)利用的城乡差异和趋势,并检查初级卒中中心(PSC)增长与 tPA 使用地理差异之间的关联。方法:我们使用 2000 年至 2010 年全国住院患者样本(NIS)的出院数据和 tPA 使用指标,并描述 PSC 增长期间 AIS 护理地理差异的时间趋势。基尼系数用于量化州一级 tPA 使用的城乡不平等(从最大潜在城乡不平等的 0% 到 100%)。 结果:2001 年至 2010 年间,914,500 例 AIS 病例中,2.3% (n 5, 21, 190) 接受了 tPA。 tPA 的城乡差距进一步扩大:城市医院的 tPA 使用量 (1.17%-4.87%) 是农村医院 (0.87%-1.59%) 的四倍。在拥有 NIS 数据的 33 个州中,有 15 个州的城乡不平等程度从 2004 年到 2010 年至少达到了 75%。结论:用于 AIS 的 tPA 使用的地理差异正在增加。有必要更好地了解 tPA 使用的效应因素,以确保美国所有社区都能公平地获得 tPA 治疗。
Objective: To explore rural-urban differences and trends in tissue plasminogen activator (tPA) utilization among acute ischemic stroke (AIS) patients and examine the association between primary stroke center (PSC) growth and geographic disparity in tPA use.Methods: We used hospital discharge data from the National Inpatient Sample (NIS) from 2000 to 2010 and indicators of tPA utilization and describe temporal trends in geographic disparities in AIS care during PSC growth. The Gini coefficient was used to quantify rural-urban inequity in tPA use at the state level (from 0% to 100% of maximum potential rural-urban inequity) in tPA use.Results: Of 914,500 cases of AIS between 2001 and 2010, 2.3% (n 5 21, 190) received tPA. The rural-urban disparity in tPA worsened: tPA use in urban hospitals quadrupled (1.17%-4.87%) compared to rural hospitals (0.87%-1.59%). Of 33 states with NIS data, 15 reached at least 75% of the maximum rural-urban inequality from 2004 to 2010.Conclusions: Geographic disparities in tPA use for AIS are increasing. Greater understanding of the effectors of tPA utilization is necessary to ensure that access to tPA treatment is equitable for all communities in the United States.