Neural properties of cultured human endocrine tumor cells of proposed neural crest origin.

Neural properties of cultured human endocrine tumor cells of proposed neural crest origin.
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所培养的神经嵴起源的人内分泌肿瘤细胞的神经特性。

DOI:
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发表时间:
1976
期刊:
影响因子:
56.9
通讯作者:
H. Wolfe
H. Wolfe
中科院分区:
综合性期刊1区
文献类型:
--
作者:
A. Tischler;M. Dichter;B. Biales;R. DeLellis;H. Wolfe

文献摘要

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细胞从人类内分泌肿瘤的建议神经嵴起源-五嗜铬细胞瘤,甲状腺髓样癌,和两个支气管类癌-生长在单层培养。所有9个肿瘤的细胞,包括上皮形式的甲状腺髓样癌和支气管类癌细胞,以及上皮和神经元样嗜铬细胞瘤细胞表现出全有或全无,短时间的动作电位。
Cells from human endocrine tumors of proposed neural crest origin--five pheochromocytomas, two medullary carcinomas of the thyroid, and two bronchial carcinoids--were grown in monolayer culture. Cells from all nine tumors, including epithelial forms of medullary carcinoma of the thyroid and bronchial carcinoid cells, and epithelial and neuron-like pheochromocytoma cells demonstrated all-or-nothing, short-duration action potentials.