Towards quality assurance and quality control in untargeted metabolomics studies
Towards quality assurance and quality control in untargeted metabolomics studies
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DOI：
10.1007/s11306-018-1460-7
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发表时间：
2019-01-01
期刊：
影响因子：
3.6
通讯作者：
Zanetti, Krista A.
中科院分区：
文献类型：
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作者：
Beger, Richard D.;Dunn, Warwick B.;Zanetti, Krista A.
我们在此描述了社区参与工作的商定首要开发步骤和优先目标，以解决非靶向代谢组学研究中质量保证（QA）和质量控制（QC）方面的当前挑战。这包括（1）代谢组学界在2015年回复的QA和QC问卷，其中建议对代谢组学界进行教育，开发适当的标准参考物质，并为实验室应用QA和QC提供激励措施;（2）一个2-非靶向代谢组学研究的质量保证和质量控制智囊团“在国家癌症研究所的Shady格罗夫校区举行及（3）成立代谢组学质量保证及质量控制联盟（mQACC），以协调方式推动发展。
We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has included (1) a QA and QC questionnaire responded to by the metabolomics community in 2015 which recommended education of the metabolomics community, development of appropriate standard reference materials and providing incentives for laboratories to apply QA and QC; (2) a 2-day Think Tank on Quality Assurance and Quality Control for Untargeted Metabolomic Studies' held at the National Cancer Institute's Shady Grove Campus and (3) establishment of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) to drive forward developments in a coordinated manner.