Incidence, aetiology and mortality rate of acute pancreatitis over 10 years in a defined urban population in Sweden
Incidence, aetiology and mortality rate of acute pancreatitis over 10 years in a defined urban population in Sweden
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DOI：
10.1046/j.1365-2168.1999.01049.x
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发表时间：
1999-04-01
影响因子：
9.6
通讯作者：
Borgström, A
中科院分区：
文献类型：
--
作者：
Appelros, S;Borgström, A
背景：急性胰腺炎的年发病率范围很广（5-50/100000）。此外，在不同的报告中，主要病因也各不相同。本研究是为了建立目前的发病率，病因学和相关的死亡率在一个定义population.Methods：一个回顾性研究的急性胰腺炎的所有病例承认超过10年的时间内，一个单一的机构进行。结果：共记录急性胰腺炎883例，其中首次发病547例。首次发作的年发生率为每10万人23.4例。包括复发在内，发病率为38.2/10万。胆道疾病是首次发作的主要病因，而酒精是复发的主要因素。人群中急性胰腺炎的平均年死亡率为1.3/100000。在31例死于急性胰腺炎的患者中，只有15例在死亡前被诊断出来。复发性疾病的死亡率为0.3%.In 12例胰腺炎与胰腺癌。结论：重要的是要区分第一次攻击和复发，因为发病率和病因数字的影响，这是很重要的，包括尸检和法医材料在人口为基础的死亡率研究。
Background: There is a wide range (5-50 per 100 000) in the reported annual incidence of acute pancreatitis. Furthermore, the predominant aetiology varies in different reports. This study was undertaken to establish the current incidence, aetiology and associated mortality rate in a defined population.Methods: A retrospective study of all cases of acute pancreatitis admitted over a 10-year period to a single institution was performed. In addition the autopsy and forensic materials were reviewed.Results: Altogether 883 attacks of acute pancreatitis were recorded, of which 547 were first attacks. The annual incidence of first attacks was 23.4 per 100 000. Including relapses, the incidence was 38.2 per 100 000. Biliary disease was the main aetiological factor in first attacks whereas alcohol was the predominant factor when relapses were included. The mean annual mortality rate for acute pancreatitis in the population was 1.3 per 100 000. Of 31 patients who died from acute pancreatitis only 15 were diagnosed before death. For recurrent disease the mortality rate was 0.3 per cent. In 12 patients the pancreatitis was associated with pancreatic carcinoma.Conclusion: It is important to differentiate between first attacks and relapses, since both incidence and aetiology figures are influenced by this, and it is important to include autopsy and forensic material in population-based mortality studies.