Thyroid MIBG uptake in Parkinson's disease with diabetes mellitus
Thyroid MIBG uptake in Parkinson's disease with diabetes mellitus
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DOI：
10.1007/s10286-013-0204-z
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发表时间：
2013-08-01
影响因子：
5.8
通讯作者：
Kim, Hee-Tae
中科院分区：
文献类型：
--
作者：
Jang, Wooyoung;Kim, Joong-Seok;Kim, Hee-Tae
在我们的工作中，我们研究了甲状腺和心脏 MIBG 的摄取作为潜在的差异标记。我们观察到 PD 和糖尿病 CAN 中 MIBG 的心脏摄取减少，这与之前的研究一致。然而，PD 组和糖尿病心脏自主神经病变组之间在早期和延迟甲状腺 MIBG 摄取方面存在显着差异，因为在 PD 中观察到甲状腺 MIBG 摄取减少，但在糖尿病自主神经病变中则没有。因此，我们建议，当帕金森症与 DM 一起出现时，该参数可以作为识别帕金森症的标志。
In our work, we investigated thyroid and cardiac MIBG uptake as potential differential markers. We observed reduced cardiac uptake of MIBG in PD and diabetic CAN, in agreement with the previous studies. However, there was a significant difference between the PD and diabetic cardiac autonomic neuropathy groups with respect to early and delayed thyroid MIBG uptake, in that reduced thyroid MIBG uptake was seen in PD but not in diabetic autonomic neuropathy. We therefore propose that this parameter could be a marker for identifying parkinsonism when it presents together with DM.