Measuring Cochlear Duct Length - a historical analysis of methods and results.
Measuring Cochlear Duct Length - a historical analysis of methods and results.
复制标题
DOI：
10.1186/s40463-017-0194-2
复制
发表时间：
2017-03-07
期刊：
影响因子：
--
通讯作者：
Agrawal SK
中科院分区：
文献类型：
--
作者：
Koch RW;Ladak HM;Elfarnawany M;Agrawal SK
人工耳蜗导管长度（CDL）一直是衡量人工耳蜗发展和进步的重要指标。新兴文献表明，CDL可用于术前设置，以选择适当大小的电极和开发定制的频率图。为了改善术后结果和开发新的电极技术，必须验证测量CDL的方法以允许在临床使用。本综述的目的是评估用于计算CDL的各种技术，并为读者提供足够的信息，以便就如何进行测量CDL的未来研究做出明智的决定。随着技术的发展，测量CDL的方法、用于捕获图像的方式以及测量的位置都发生了变化。随着近年来计算机断层扫描（CT）成像取代组织学切片的普及和进步，由于CT无法观察耳蜗内结构，CDL的测量一直集中在侧壁（LW）而不是Corti器官（OC）。通过对直接从组织学测量CDL、间接重建耳蜗形状、基于螺旋系数确定CDL等方法结果的分析，确定三维重建法是测量CDL最可靠的方法。三维重建提供了良好的耳蜗可视化，避免了其他方法中明显的错误。由于不同方法的数量和精度不同，将来必须遵循一定的指导方针，以便在研究之间直接比较CDL值。在总结和分析了CDL测量的有趣历史之后，强调了标准化指南的使用以及CDL对未来人工耳蜗发展的重要性。
Cochlear Duct Length (CDL) has been an important measure for the development and advancement of cochlear implants. Emerging literature has shown CDL can be used in preoperative settings to select the proper sized electrode and develop customized frequency maps. In order to improve post-operative outcomes, and develop new electrode technologies, methods of measuring CDL must be validated to allow usage in the clinic. The purpose of this review is to assess the various techniques used to calculate CDL and provide the reader with enough information to make an informed decision on how to conduct future studies measuring the CDL. The methods to measure CDL, the modality used to capture images, and the location of the measurement have all changed as technology evolved. With recent popularity and advancement in computed tomography (CT) imaging in place of histologic sections, measurements of CDL have been focused at the lateral wall (LW) instead of the organ of Corti (OC), due to the inability of CT to view intracochlear structures. After analyzing results from methods such as directly measuring CDL from histology, indirectly reconstructing the shape of the cochlea, and determining CDL based on spiral coefficients, it was determined the three dimensional (3D) reconstruction method is the most reliable method to measure CDL. 3D reconstruction provides excellent visualization of the cochlea and avoids errors evident in other methods. Due to the number of varying methods with varying accuracies, certain guidelines must be followed in the future to allow direct comparison of CDL values between studies. After summarizing and analyzing the interesting history of CDL measurements, the use of standardized guidelines and the importance of CDL for future cochlear implant developments is emphasized for future studies.